Xeroderma pigmentosum with a giant cutaneous horn
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CitationAkan, M., Yıldırım, S., Avcı, G. ve Aköz, T. (2001). Xeroderma pigmentosum with a giant cutaneous horn. Annals of plastic surgery. 46(6), s. 665-666.
Cornu cutaneum or cutaneous horn is the clinical description of a hyperproliferation of compact keratin in response to a wide array of underlying benign or malignant pathological changes. 1 Cornu cutaneum refers to a reaction pattern rather than a specific lesion. Different types of skin lesions underlie cutaneous horns such as keratoses, sebaceous molluscum, verruca, trichilemma, Bowen’s disease, epidermoid carcinoma, malignant melanoma, and basal cell carcinoma. A cutaneous horn more than 1 cm in height is rare, because surgeons remove these horns early. 2 Four main features are associated with a premalignant or malignant histopathological change at the base of a cutaneous horn: patient age, sex, site, and geometry of the lesion. The mean age of patients whose cutaneous horns showed a premalignant or malignant base pathology was 8.9 years older than the mean age of patients in whom the base pathology was benign. Men are more likely to develop a cutaneous horn with a premalignant or malignant base pathology. More than 70% of all premalignant or malignant lesions are found on the nose, pinnae, back of hands, scalp, forearms, and the face, and a cutaneous horn found at these sites is 2.1 times more likely to have derived from a premalignant or malignant base than from any other part of the body) 3. Lesions with a wide base or a low height-to-base ratio were markedly more likely to show a premalignant or malignant base pathology.
SourceAnnals of Plastic Surgery
- Makale Koleksiyonu 
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