Protective effects of L-arginine on rat terminal ileum subjected to ischemia/reperfusion
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CitationSayan, H., Ozacmak, V.H., Altaner, S., Aktas, R.G. ve Arslan, S.O. (2008). Protective effects of L-arginine on rat terminal ileum subjected to ischemia/reperfusion. Journal of Pediatric Gastroenterology and Nutrition, WoltersKluwer. 46(1), s. 29-35.
Studies have shown that nitric oxide (NO) may play a major role in sustaining mucosal integrity; however, NO has been also implicated in the pathogenesis of ischemia/reperfusion (I/R)–related tissue injury. We investigated the effects of L-arginine and NG-nitro L-arginine methyl ester (L-NAME) on the acetylcholine-induced contractile response of ileum and the levels of malondialdehyde (MDA) and reduced glutathione (GSH). Histopathological changes were also evaluated in ileal preparations.
- Makale Koleksiyonu 
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