Aortic elastic properties in patients with venous thromboembolism
AuthorEkşi Duran, Nilüfer
Aykan, Ahmet Çağrı
Gürsoy, M. Ozan
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CitationDuran, N. E., Oğuz, E., Duran, İ., Ayhan, A. C., Ertürk, E., Bayram, Z., Gürsoy, M. O., Biteker, M., Karavelioğlu, Y., Kaya, H. ve Özkan, M. (2010). Aortic elastic properties in patients with venous thromboembolism. Phlebology. 25(5), s. 246-251.
Objectives: The relationship between venous thrombosis (VT) and atherosclerosis is controversial in recent studies. Aortic elastic properties have a predictive value in detecting early stages of atherosclerosis. The aim of this study is to evaluate the relationship between aortic elastic properties and VT. Methods: Elastic properties of aorta in patients with spontaneous VT, without history of known cardiovascular disease and cardiovascular risk factors (n: 31), and in healthy subjects without cardiovascular risk factors (n: 30) were compared. Elastic properties of the aorta were assessed with transthoracic echocardiography. Results: A significant increase in aortic stiffness index (6.5 ± 1.0 versus 6 ± 0.7, P = 0.03) and a significant decrease in aortic strain and aortic distensibility were found in patients with VT compared with healthy subjects (8.4 ± 7 versus 13 ± 8, P = 0.01, 4.9 ± 4.8 versus 6.5 ± 4.4, P = 0.03, respectively). Conclusions: Elastic properties of aorta in patients with spontaneous VT were impaired. These results may support the role of endothelial dysfunction in the pathogenesis of VT.
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