Is there any maximum standardized uptake value variation among positron emission tomography scanners for mediastinal staging in non-small cell lung cancer?
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Citationİskender, İ., Kadıoğlu, S. Z., Koşar, A., Atasalihi, A. ve Kir, A. (2011). Is there any maximum standardized uptake value variation among positron emission tomography scanners for mediastinal staging in non-small cell lung cancer. Interactive Cardiovascular and Thoracic Surgery. 12, s. 965-999.
The maximum standardized uptake value (SUVmax) varies among positron emission tomography-integrated computed tomography (PETyCT) centers in the staging of non-small cell lung cancer. We evaluated the ratio of the optimum SUV cut-off for the lymph nodes to the max median SUV of the primary tumor max max max (ratioSUV ) to determine SUV variations between PETyCT scanners. The previously described PET predictive ratio (PPR) was also evaluated. PETyCT and mediastinoscopy andyor thoracotomy were performed on 337 consecutive patients between September 2005 and March 2009. Thirty-six patients were excluded from the study. The pathological results were correlated with the PETyCT findings. Histopathological examination was performed on 1136 N2 lymph nodes using 10 different PETyCT centers. The majority of patients (group A: 240) used the same PETyCT scanner at four different centers. Others patients were categorized as group B. The ratioSUV for groups A and B was 0.18 and 0.22, respectively. The same ratio for centers 1, 2, 3 and 4 was 0.2, 0.21, 0.21, and 0.23, max respectively. The optimal cut-off value of the PPR to predict mediastinal lymph node pathology for malignancy was 0.49 (likelihood ratio q2.02; sensitivity 70%, specificity 65%). We conclude that the ratioSUV was similar for different scanners. Thus, SUV is a valuable cut- max max off for comparing-centers.
SourceInteractive Cardiovascular and Thoracic Surgery
- Makale Koleksiyonu