The rate of insulin nonpersistence among patients with type II diabetes who were first started on insulin treatment [İlk Kez İnsülin Tedavisi Başlanan Tip 2 Diyabetik Hastalarda İnsülin Bırakma Oranı]
Objective: Our aim in this study is to assess the rate and possible causes of nonpersistence among patients with diabetes who have received standard insulin education for their insulin treatment. Material and Methods: 700 patients with type II diabetes, who were started on insulin treatment by outpatient clinics of Dr. Lütfi Kırdar Kartal Training and Research Hospital between 1/1/2012-1/1/2013, and who had received the same standard insulin education given by diabetes nurses, were enrolled in this study. Patients were called by the phone and a questionnaire was filled regarding patients' socio-demographic characteristics, comorbidities and patients' insulin use. We have reached 462 patients/relatives. Total of 14 patients died, and 23 patients, whose insulin treatment was nonpersistent by a physician, were excluded. 425 patients were included in the final analysis. Results: Among 425 patients, 50.8% were male, mean age was 57.7 years (±11.6 years) and average time since diabetes diagnosis was 6.6 years (±6.2 years). 57.6% were on basal, 17.9% on premixed and 24.5% were on basal-bolus insulin regimen. The rate of nonpersistence was found to be 6.2%. Non-parametric correlation tests revealed that compliance rates significantly increased with increased age (p=0.01, r=0.12). Most common causes of nonpersistence were hypoglycemia, fatigue (26.9%), feeling good and cured (23%) and difficulties in injections (15.3%) allergy 11.5%, environmental factors 7.6%, and fear of addiction 7.6%. Conclusions: Detecting the underlying causes of nonpersistence of insulin by the healthcare centers that initiated the treatment, and utilizing these data for revising standard insulin education programs could be a key factor for reaching the desired glycemic goals in patients with diabetes. © 2017 by Türkiye Klinikleri.
SourceTurkiye Klinikleri Journal of Medical Sciences
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