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Yayın The effects of non-steroid anti-inflammatory drugs Rofecoxib and Valdecoxib on DSPC model membranes: FT-IR and DSC study(Maltepe Üniversitesi, 2014) Rachkauskas, Richardas; Banerjee, Sreeparna; Severcan, FerideCelecoxib (CLX), rofecoxib (RFX) and valdecoxib (VLX) belong to a family of NSAIDs,which are selective COXV2 inhibitors. While these drugs are established analgesics, they also have a number of pleiotropic effects such as cancer chemoprevention, occasionally in a COXV2 independent manner.