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Yayın The effects of non-steroid anti-inflammatory drugs Rofecoxib and Valdecoxib on DSPC model membranes: FT-IR and DSC study(Maltepe Üniversitesi, 2014) Rachkauskas, Richardas; Banerjee, Sreeparna; Severcan, FerideCelecoxib (CLX), rofecoxib (RFX) and valdecoxib (VLX) belong to a family of NSAIDs,which are selective COXV2 inhibitors. While these drugs are established analgesics, they also have a number of pleiotropic effects such as cancer chemoprevention, occasionally in a COXV2 independent manner.Yayın Molecular characterization of the effects of valdecoxib on colon cancer cell lines (HT29 & SW620) using ATR-FTIR spectroscopy(Maltepe Üniversitesi, 2014) İnan Genç, Aysun; Severcan, Feride; Banerjee, SreeparnaColorectal cancer is the third most common malignancy and the fourth most frequent cause of cancer deaths worldwide, with 945,000 estimated new cases and 492,000 deaths per year in industrialized countries.