Do deferoxamine, ticlopidine or trimetazidine prevent sevoflurane nephrotoxicity? An electron microscopic study
dc.authorid | 0000-0002-4474-7371 | en_US |
dc.contributor.author | Karamanlıoğlu, B. | |
dc.date.accessioned | 2024-07-12T21:10:13Z | |
dc.date.available | 2024-07-12T21:10:13Z | |
dc.date.issued | 2003 | en_US |
dc.department | Fakülteler, Tıp Fakültesi | en_US |
dc.description.abstract | Sevoflurane is a common anesthetic drug. Several biochemical, pharmacologic and physiologic studies have showed nephrotoxicity of Sevoflurane[1,2,3]. Histopathologic studies reported tubular damage and tubular cellular hyperplasia after the administration of Sevoflurane[4]. Deferoxamine(DFO) is known to protect against myoglobinuric acute renal failure[5]. It has been suggested that Ticlopidine(TIC) does not prevent nephropathies but has beneficial effects[6]. Fang et al. showed that TIC inhibited mesangial cell proliferation and collagen synthesis[7]. There is another study reporting that TIC induces acute interstitial nephrite and cause an increase of the number of lymphocytes and eosinophil leucocytes in interstitial tissue[8]. Trimetazidine(TMZ) has anti-ischemic effects and protects tissue damage in kidney[5, 9, 10, 11]. These studies lead us to investigate if DFO, TIC or TMZ can prevent the nephrotoxicity of Sevoflurane at morphologic level. | en_US |
dc.identifier.citation | Karamanlıoğlu, B. ve Aktaş, R. G. (2003). Do deferoxamine, ticlopidine or trimetazidine prevent sevoflurane nephrotoxicity? An electron microscopic study. Microscopy and Microanalysis, Cambridge University Press. 9(2), s. 1428-1429. | en_US |
dc.identifier.endpage | 1429 | en_US |
dc.identifier.issn | 1435-8115 | |
dc.identifier.issue | 2 | en_US |
dc.identifier.scopusquality | Q3 | en_US |
dc.identifier.startpage | 1428 | en_US |
dc.identifier.uri | https://www.cambridge.org/core/journals/microscopy-and-microanalysis/article/do-deferoxamine-ticlopidin-or-trimetazidine-prevent-sevoflurane-nephrotoxicity-an-electron-microscopic-study/226E6AEA4E9FD98B471ABE350D92C5D4 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12415/4214 | |
dc.identifier.volume | 9 | en_US |
dc.institutionauthor | Aktaş, Ranan Gülhan | |
dc.language.iso | en | en_US |
dc.publisher | Cambridge University Press | en_US |
dc.relation.ispartof | Microscopy and Microanalysis | en_US |
dc.relation.isversionof | 10.1017/S1431927603447144 | en_US |
dc.relation.publicationcategory | Uluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanı | en_US |
dc.rights | CC0 1.0 Universal | * |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights.uri | http://creativecommons.org/publicdomain/zero/1.0/ | * |
dc.snmz | KY02939 | |
dc.title | Do deferoxamine, ticlopidine or trimetazidine prevent sevoflurane nephrotoxicity? An electron microscopic study | en_US |
dc.type | Article | |
dspace.entity.type | Publication |