Şahin, S.Tan, D.Karşida?, S.2024-07-122024-07-1220061016-51342-s2.0-33744783705https://hdl.handle.net/20.500.12415/7539Alien hand syndrome (AHS) refers to the occurrence of apparently purposeful movements in the hand which are independent of volitional control. Two subtypes of AHS have been proposed: 'anterior-motor' subtype with grasp reflex and impulsive manipulation of tools by the dominant hand and 'posterior-sensorial' subtype with hemispheric neglection. Here in a case of Corticobasal Ganglionic degeneration (CBGD), we report, anteriortype AHS with symptoms of impulsive grasping and apraxia in his left hand. Cranial magnetic resonance imaging (MRI) showed diffuse atrophy of cortex and periventricular millimetric ischemic-gliotic lesions. Single - photon emission computed tomography (SPECT) analysis labelled with 99m technetium hexamethylpropyleneamineoxime (Tc-99m-HMPAO) demonstrated hypoperfusion in the left frontal lobe and the temporo-parietal areas dominantly in the left hemisphere. In this article, we aim to review the literature about AHS based on our case's findings.trinfo:eu-repo/semantics/closedAccessAlien Hand SyndromeApraxiaBrain AtrophyCognitionHand DiseaseHumanMotor DysfunctionNuclear Magnetic Resonance ImagingReviewSingle Photon Emission Computer TomographyReview Article934N/A9118