Keskin Kaplan, AşkınSezgin, Gülbüz2024-07-122024-07-1220232146-995410.37989/gumussagbil.1357513https://doi.org/10.37989/gumussagbil.1357513https://search.trdizin.gov.tr/yayin/detay/1199753https://hdl.handle.net/20.500.12415/9766This study aimed to assess awareness of Porphyria Disease among primary care physicians and investigate its diagnosis and management. This study is a cross-sectional online survey conducted with the participation of 390 primary care physicians in Turkey. Participants were recruited through online platforms, including WhatsApp and email groups. Participants who provided consent were administered an online electronic survey created using Google Forms. Data were analyzed using IBM SPSS Statistics version 21.0. Ethical approval was granted by the Clinical Research Ethics Committee. With an average of 14.13±9.56 years of medical experience, participants included 47.4% family medicine specialists, 38.5% family physicians, and 14.4% emergency medicine specialists. Only 10.5% of the total physicians reported evaluating patients with suspected Porphyria. Severe abdominal pain was the predominant symptom, cited by 78% of participants, while just 5.4% had previously been diagnosed with Porphyria. Notably, family medicine specialists exhibited a significantly higher inclination for both preliminary (p<0.001) and confirmed (p=0.041) porphyria diagnosis. 81.0% of physicians considered Familial Mediterranean Fever as part of their differential diagnosis when assessing patients with porphyria symptoms. In conclusion, our study highlights an increased awareness of Porphyria among primary care physicians, likely owing to advancements in diagnostic methods. However, the need to raise awareness remains, given its crucial role in diagnosis. Therefore, it is essential to involve primary care physicians, particularly family medicine specialists and emergency medicine specialists, in porphyria education and awareness initiatives. These efforts can ensure accurate diagnoses and better care for patients affected by this rare disease.eninfo:eu-repo/semantics/openAccessArticle8763870119975312