Altinmakas, SDagdeviren, BUyan, CKeser, NGumus, VPektas, O2024-07-122024-07-1220000167-527310.1016/S0167-5273(00)00226-62-s2.0-0343442382https://dx.doi.org/10.1016/S0167-5273(00)00226-6https://hdl.handle.net/20.500.12415/8080Dobutamine stress echocardiography is widely used to predict reversible left ventricular dysfunction, but evaluation with this method is subjective. Pulsed-wave tissue Doppler imaging is a new technique that allows to obtain quantitative data on wall motion velocities of different myocardial segments through sample-volume placement. Therefore, this tool in combination with DSE may be suitable for identifying viability in asynergic myocardium. To evaluate this, in 40 patients (mean age 57+/-9) with resting dyssynergy (akinesis in 52, hypokinesis in 30) baseline wall motion scores and tissue Doppler variables were collected before and after 5 min infusion of 10 mu g/kg per min dobutamine. Forty-six of 82 segments were classified as viable (a reduction in segmental score of at least one grade) according to follow-up echocardiography that was performed 4 weeks after revascularization. While myocardial S velocity percent increase in viable segments was 45+/-10, the increase was 25+/-12 in necrotic segments (n=36) during 10 mu g dobutamine infusion (P=0.0001). Assuming 35% as a cut-off for viability the increase in S velocities by DSE yielded an 89% sensitivity and 86% specificity for predicting post-revascularization functional recovery. In conclusion, pulsed-wave tissue Doppler imaging of asynergic myocardium during dobutamine stress echocardiography can identify the viability quantitatively. (C) 2000 Elsevier Science Ireland Ltd. All nights reserved.eninfo:eu-repo/semantics/closedAccesstissue Dopplerviabilitydobutamine stress testArticle1132.Mar10962109Q110774WOS:000089568800001Q3