Cortegiani, A.Gregoretti, C.Neto, A. S.Hemmes, S. N. T.Ball, L.Canet, J.Hiesmayr, M.Hollmann, M. W.Mills, G. H.Melo, M. F. V.Putensen, C.Schmid, W.Severgnini, P.Wrigge, H.de Abreu, M. GamaSchultz, M. J.Pelosi, P.Kroell, WolfgangMetzler, HelfriedStruber, GerdWegscheider, ThomasGombotz, HansHiesmayr, MichaelSchmid, WernerUrbanek, BernhardKahn, DavidMomeni, MonaPospiech, AudreyLois, FernandeForget, PatriceGrosu, IrinaPoelaert, Janvan Mossevelde, Veerlevan Malderen, Marie-ClaireDylst, Dimitrivan Melkebeek, JeroenBeran, Maudde Hert, StefanDe Baerdemaeker, LucHeyse, BjornVan Limmen, JurgenWyffels, PietJacobs, TomRoels, NathalieDe Bruyne, Annvan de Velde, StijnLeva, BrigitteDamster, SandrinePlichon, BenoitJuros-Zovko, MarinaDjonovic-Omanovic, DejanaPernar, SelmaZunic, JosipMiskovic, PetarZilic, AntonioKvolik, SlavicaIvic, DubravkaAzenic-Venzera, DarijaSkiljic, SonjaVinkovic, HrvojeOputric, IvanaJuricic, KazimirFrkovic, VedranKopic, JasminkaMirkovic, IvanKaranovic, NenadCarev, MladenDropulic, NatasaSaric, Jadranka PavicicErceg, GorjanaDvorscak, Matea BogdanovicMazul-Sunko, BrankaPavicic, Anna MarijaGoranovic, TanjaMaldini, BrankaRadocaj, TomislavGavranovic, ZeljkaMladic-Batinica, IngaSehovic, MirnaStourac, PetrHarazim, HanaSmekalova, OlgaKosinova, MartinaKolacek, TomasHudacek, KamilDrab, MichalBrujevic, JanVitkova, KaterinaJirmanova, KaterinaVolfova, IvanaDzurnakova, PaulaLiskova, KatarinaDudas, RadovanFilipsky, Radekel Kafrawy, SamirAbdelwahab, Hisham HosnyMetwally, TarekAbdel-Razek, AhmedEl-Shaarawy, Ahmed MostafaHasan, Wael FathyAhmed, Ahmed GoudaYassin, HanyMagdy, MohamedAbdelhady, MahdyMahran, MohamedHerodes, EikoKivik, PeeterOganjan, JuriAun, AnnikaSormus, AlarSarapuu, KailiMall, MerilinKarjagin, JuriFutier, EmmanuelPetit, AntoineGerard, AdelineMarret, EmmanuelSolier, MarcJaber, SamirPrades, AlbertKrassler, JensMerzky, SimoneUhlig, ChristopherKiss, ThomasBundy, AnetteBluth, ThomasGueldner, AndreasSpieth, PeterScharffenberg, MartinThiem, Denny TranKoch, TheaTreschan, TanjaSchaefer, MaximilianBastin, BeaGeib, JohannWeiss, MartinKienbaum, PeterPannen, BenediktGottschalk, AndreKonrad, MirjaWesterheide, DianaSchwerdtfeger, BenWrigge, HermannSimon, PhilippReske, AndreasNestler, ChristianValsamidis, DimitriosStroumpoulis, KonstantinosAntholopoulos, GeorgiosAndreou, AntonisKarapanos, DimitrisTheodorak, KassianiGkiokas, GeorgiosTasoulis, Marios-KonstantinosSidiropoulou, TatianaZafeiropoulou, FoteiniFlorou, PanagiotaPandazi, AggelikiTsaousi, GeorgiaNouris, ChristosPourzitaki, ChryssaBystritski, DmitriPizov, ReuvenEden, AriehPesce, Caterina ValeriaCampanile, AnnamariaMarrella, AntonellaGrasso, SalvatoreDe Michele, MicheleBona, FrancescoGiacoletto, GianmarcoSardo, ElenaSottosanti, Luigi Giancarlo VicariSolca, MaurizioVolta, Carlo AlbertoSpadaro, SavinoVerri, MarcoRagazzi, RiccardoZoppellari, RobertoCinnella, GildaRaimondo, PasqualeLa Bella, DanielaMirabella, LuciaD'antini, DavideMolin, AlexandreBrunetti, IoleGratarola, AngeloPellerano, GiuliaSileo, RosannaPezzatto, StefanoMontagnani, LucaPasin, LauraLandoni, GiovanniZangrillo, AlbertoBeretta, LuigiDi Parma, Ambra LiciaTarzia, ValentinaDossi, RobertoSassone, Marta EugeniaSances, DanieleTredici, StefanoSpano, GianlucaCastellani, GianlucaDelunas, LuigiPeradze, SopioVenturino, MarcoArpino, InesSher, SaraTommasino, ConcezioneRapido, FrancescaMorelli, PaolaVargas, MariaServillo, GiuseppeRaineri, Santi MaurizioMontalto, FrancescaRussotto, VincenzoGiarratano, AntoninoBaciarello, MarcoGenerali, MichelaCerati, GiorgiaLeykin, YigalBressan, FilippoBartolini, VittoriaZamidei, LuciaBrazzi, LucaLiperi, CorradoSales, GabrielePistidda, LauraSevergnini, PaoloBrugnoni, ElisaMusella, GiuseppeBacuzzi, AlessandroMuhardri, DalipGecaj-Gashi, AgretaSada, FatosBytyqi, AdemKarbonskiene, AurikaAukstakalniene, RutaTeberaite, ZivileSalciute, ErikaTikuisis, RenatasMiliauskas, PovilasJurate, SipylaiteKontrimaviciute, EgleTomkute, GabijaXuereb, JohnBezzina, MaureenBorg, Francis JosephHemmes, SabrineSchultz, MarcusHollmann, MarkusWiersma, IreneBinnekade, JanBos, LieuweBoer, ChristaDuvekot, Annein 't Veld, BasWerger, AliceDennesen, PaulSeverijns, CharlotteDe Jong, JasperHering, Jensvan Beek, RienkIvars, StefanJammer, IbBreidablik, AlenaHodt, Katharina SkirstadFjellanger, FrodeAvalos, Manuel VicoMellin-Olsen, JannickeAndersson, ElisabethShafi-Kabiri, AmirMolina, RubyWutai, StanleyMorais, ErickTareco, GloriaFerreira, DanielAmaral, JoanaGoncalves Castro, Maria de LurdesCadilha, SusanaAppleton, SofiaParente, SuzanaCorreia, MarianaMartins, DiogoMonteirosa, AngelaRicardo, AnaRodrigues, SaraHorhota, LucianGrintescu, Ioana MarinaMirea, LilianaGrintescu, Ioana CristinaCorneci, DanNegoita, SilviusDutu, MadalinaGarotescu, Ioana PopescuFilipescu, DanielaProdan, Alexandru BogdanDroc, GabrielaFota, RuxandraPopescu, MihaiTomescu, DanaPetcu, Ana MariaTudoroiu, Marian IrinelMoise, AlidaGuran, Catalin-TraianGherghina, IorelCostea, DanCindea, IuliaCopotoiu, Sanda-MariaCopotoiu, RuxandraBarsan, VictoriaTolcser, ZsoltRiciu, MagdaMoldovan, Septimiu GheorgheVeres, MihalyGritsan, AlexeyKapkan, TatyanaGritsan, GalinaKorolkov, OlegKulikov, AlexanderLubnin, AndreyOvezov, AlexeyProkoshev, PavelLugovoy, AlexanderAnipchenko, NataliaBabayants, AndreyKomissarova, IrinaZalina, KarginovaLikhvantsev, ValeryFedorov, SergeiLazukic, AleksandraPejakovic, JasminaMihajlovic, DunjaKusnierikova, ZuzanaZelinkova, MariaBruncakova, KatarinaPolakovicova, LenkaSobona, VilliamNovak-Supe, BarbkaPekle-Golez, AnaJovanov, MiroljubStrazisar, BrankaMarkovic-Bozic, JasminaNovak-Jankovic, VesnaVoje, MincaGrynyuk, AndriyKostadinov, IvanSpindler-Vesel, AlenkaMoral, VictoriaCarmen Unzueta, MariPuigbo, CarlosFava, JosepMoret, EnriqueRodriguez Nunez, MonicaSendra, MarBrunelli, AndreaRodenas, FredericMonedero, PabloHidalgo Martinez, FranciscoYepes Temino, Maria JoseMartinez Simon, Antoniode Abajo Larriba, AnaLisi, AlbertoPerez, GiselaMartinez, RaquelGranell, ManuelTatay Vivo, JoseSaiz Ruiz, Cristinade Andres Ibanez, Jose AntonioPastor, ErnestoSoro, MarinaFerrando, CarlosDefez, MarioAldecoa Alvares-Santullano, CesarPerez, RocioRico, JesusJawad, MonirSaeed, YousifGillberg, LarsBengisun, Zuleyha KazakKazbek, Baturay KansuCoskunfirat, NesilBoztug, NevalSanli, SuatYilmaz, MuratHadimioglu, NecmiyeSenturk, Nuzhet MertCamci, EmreKucukgoncu, SemraSungur, ZerrinSivrikoz, NukhetOzgen, Serpil UstalarToraman, FevziSelvi, OnurSenturk, OzgurYildiz, MineKuvaki, BaharGunenc, FerimKucukguclu, SemihOzbilgin, SuleMaral, JaleCanli, SeydaArun, OguzhanSaltali, AliAydogan, EyupAkgun, Fatma NurSanlikarip, CerenKaraman, Fatma MineMazur, AndriyVorotyntsev, SergiyRousseau, GuyBarrett, ColinStancombe, LuciaShelley, BenScholes, HelenLimb, JamesRafi, AmirWayman, LisaDeane, JillRogerson, DavidWilliams, JohnYates, SusanRogers, ElainePulletz, MarkMoreton, SarahJones, StephanieVenkatesh, SureshBurton, MaudrianBrown, LucyGoodall, CaitRucklidge, MatthewFuller, DebbieNadolski, MariaKusre, SandeepLundberg, MichaelEverett, LynnNutt, HelenZuleika, MakaCarvalho, PeterClements, DeborahCreagh-Brown, BenWatt, PhilipRaymode, ParizadePearse, RupertMohr, OttoRaj, AshokCreary, ThaisChishti, AhmedBell, AndreaHigham, CharleyCain, AlistairGibb, SarahMowat, StephenFranklin, DanielleWest, ClaireMinto, GaryBoyd, NicholasMills, GaryCalton, EmilyWalker, RachelMackenzie, FelicityEllison, BranwenRoberts, HelenChikungwa, MosesJackson, ClareDonovan, AndrewFoot, JayneHoman, ElizabethMontgomery, JanePortch, DavidMercer, PaulinePalmer, JanetPaddle, JonathanFouracres, AnnaDatson, AmandaAndrew, AlysonWelch, LeanneRose, AlastairVarma, SandeepSimeson, KarenRambhatla, MrutyunjayaSusarla, JaysimhaMarri, SudhakarKodaganallur, KrishnanDas, AshokAlgarsamy, ShivarajanColley, JulieDavies, SimonSzewczyk, MargaretSmith, ThomasFernandez-Bustamante, AnaLuzier, ElizabethAlmagro, AngelaMelo, Marcos VidalFernando, LuizSulemanji, DemetSprung, JurajWeingarten, TobyKor, DarylScavonetto, FedericaTze, Yeo2024-07-122024-07-1220190007-09121471-677110.1016/j.bja.2018.10.0632-s2.0-85058784675https://dx.doi.org/10.1016/j.bja.2018.10.063https://hdl.handle.net/20.500.12415/7824Background: The aim of this post hoc analysis of a large cohort study was to evaluate the association between night-time surgery and the occurrence of intraoperative adverse events (AEs) and postoperative pulmonary complications (PPCs). Methods: LAS VEGAS (Local Assessment of Ventilatory Management During General Anesthesia for Surgery) was a prospective international 1-week study that enrolled adult patients undergoing surgical procedures with general anaesthesia and mechanical ventilation in 146 hospitals across 29 countries. Surgeries were defined as occurring during 'daytime' when induction of anaesthesia was between 8: 00 AM and 7: 59 PM, and as 'night-time' when induction was between 8: 00 PM and 7: 59 AM. Results: Of 9861 included patients, 555 (5.6%) underwent surgery during night-time. The proportion of patients who developed intraoperative AEs was higher during night-time surgery in unmatched (43.6% vs 34.1%; P<0.001) and propensity-matched analyses (43.7% vs 36.8%; P = 0.029). PPCs also occurred more often in patients who underwent night-time surgery (14% vs 10%; P = 0.004) in an unmatched cohort analysis, although not in a propensity-matched analysis (13.8% vs 11.8%; P = 0.39). In a multivariable regression model, including patient characteristics and types of surgery and anaesthesia, night-time surgery was independently associated with a higher incidence of intraoperative AEs (odds ratio: 1.44; 95% confidence interval: 1.09-1.90; P = 0.01), but not with a higher incidence of PPCs (odds ratio: 1.32; 95% confidence interval: 0.89-1.90; P = 0.15). Conclusions: Intraoperative adverse events and postoperative pulmonary complications occurred more often in patients undergoing night-time surgery. Imbalances in patients' clinical characteristics, types of surgery, and intraoperative management at night-time partially explained the higher incidence of postoperative pulmonary complications, but not the higher incidence of adverse events.eninfo:eu-repo/semantics/closedAccessgeneral anaesthesiaintraoperative complicationspatient safetypostoperative complicationspulmonaryArticle369330770054Q1361122WOS:000458513600019Q1