Demir, DenizBalcı, A.B.Kahraman, NailSünbül, S.A.Gücü, A.Seker, I.B.Badem, SerdarYüksel, AhmetÖzyazıcıoğlu, A.F.Göncü, M.T.Demir, Deniz2024-07-122024-07-122022Demir, D., Balcı, A.B., Kahraman, N., Sünbül, S.A. vd. (2022). The comparison of del nido cardioplegia and crystalloid-based blood cardioplegia in adult isolated coronary bypass surgery: A randomized controlled trial. Nigerian Journal of Clinical Practice, Wolters Kluwer. 25(12), s. 1998-2004.1119-3077https://www.njcponline.com/article.asp?issn=1119-3077;year=2022;volume=25;issue=12;spage=1998;epage=2004;aulast=Demirhttps://hdl.handle.net/20.500.12415/3433Background and Aim: In our study, patients who underwent isolated coronary artery bypass surgery (CABG) using Del Nido cardioplegia (DNC) and crystalloid-based cold blood cardioplegia (CBC) were compared. Subject and Methods: In this study, two groups of patients who underwent isolated CABG using DNC (n = 106) and CBC (n = 107) were prospectively randomized. Groups were compared in terms of many results such as troponin T, returning spontaneous rhythm, and cardioplegia volume. Results and Conclusions: Median troponin T levels of the DNC and CBC groups were compared for the 0th hour (baseline), 12th, 36th, and 60th hours. There was no statistical difference between groups in troponin T levels of the baseline 0th hour (18[33] vs. 22[27] pg/ml; P = 0.724). Troponin T levels at the 12th hour were less in the DNC group than the CBC group but no statistical difference between the groups (790[735] vs. 826[820] pg/ml; P = 0.068), respectively. Troponin T levels at 36th and 60th hours were higher in the CBC group compared to the DNC group, and a statistical difference was observed (580[546] vs. 650[550] pg/ml; P = 0.030) and (359[395] vs. 421[400] pg/ml; P = 0.020), respectively. After X-clamping, the spontaneous rhythm rate was statistically higher in the DNC group than the CBC group (72.60% vs. 37.40%; P < 0.001). There was no statistical difference between the groups in terms of postoperative arrhythmia, hospital stay, and mortality rates (P > 0.05). Based on data we acquired from the study, we think that DNC is at least as safe and effective as CBC in adult CABG cases.eninfo:eu-repo/semantics/openAccessDel nido cardioplegiaisolated coronary artery bypassreturn spontaneous rhythmArticle200412Q3199825