Kaya, Ali HakanTekgunduza, Emre2024-07-122024-07-1220211473-05021878-168310.1016/j.transci.2021.1033132-s2.0-85119302572https://doi.org/10.1016/j.transci.2021.103313https://hdl.handle.net/20.500.12415/7503Hematopoietic stem cell transplantation associated-thrombotic microangiopathy (TA-HCT) is one of the early complications of endothelial origin in the course of HCT. Endothelial damage to the microvascular structure and the platelet-rich microthrombi, which are formed as a result of accompanying complement activation, constitute the main pathological conditions resulting TA-TMA. Early diagnosis and management are of utmost importance to prevent multi-organ failure and death. This review summarizes the current understanding of TA-TMA regarding pathogenesis, definition, differential diagnosis, risk factors, surveillance for early diagnosis and management.eninfo:eu-repo/semantics/closedAccessHematopoietic Stem Cell TransplantationThrombotic MicroangiopathyThrombocytopeniaEditorial634785151Q360WOS:000733239700043Q4