Comparison of serum androgens and endometrial thickness in obese and non-obese postmenopausal women [Obez ve obez olmayan postmenopozal hastalarda serum androjen seviyeleri ve endometrial kali{dotless}nli{dotless}gn karşi{dotless}laşti{dotless}nlmasi{dotless}]

Arikan I.I.Barut A.Arikan D.Harma M.Harma M.I.Bozkurt S.2024-07-122024-07-1220101309-039910.5152/jtgga.2010.232-s2.0-78249290536https://dx.doi.org/10.5152/jtgga.2010.23https://hdl.handle.net/20.500.12415/8286Objective: In this study, we investigated whether serum androgen levels and endometrial thickness differed in obese and non-obese women. Material and Methods: Thirtytwo non-obese (BMI <30) and 48 obese (BMI ? 30) women were enrolled. Blood samples were analyzed for testosterone, free testosterone, androstenedione, DHEAS, and SHBG, and transvaginal ultrasonography was performed. Results: Obese women had significantly higher free testosterone and endometrial thickness and significantly lower SHBG. Eight of 17 women with endometrial thickness >5 mm had significant pathology. Conclusion: These results suggest that obesity may be a risk factor for endometrial carcinoma and other pathologies in post-menopausal women through an action on androgen concentrations.trinfo:eu-repo/semantics/openAccessEndometrial thicknessObesityPostmenopauseSerum androgeneComparison of serum androgens and endometrial thickness in obese and non-obese postmenopausal women [Obez ve obez olmayan postmenopozal hastalarda serum androjen seviyeleri ve endometrial kali{dotless}nli{dotless}gn karşi{dotless}laşti{dotless}nlmasi{dotless}]Article1513Q314911