Kosif, Rengin2024-07-122024-07-122009Kosif, R. ve Aktas, R.G. (2009). Investigation of the effects of Aloe barbadensis on rat ovaries: a preliminary study. Journal of Medicinal Food, Mary Ann Liebert, Inc. and Korean Society of Food Science and Nutrition. 12(6), s. 1393-1397.1096-620X1557-7600https://www.liebertpub.com/doi/10.1089/jmf.2009.0035?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&https://hdl.handle.net/20.500.12415/3835Effects of Aloe barbadensis, a type of Aloe vera, on ovaries were investigated during pregnancy. A. vera gel, a commercial and nontherapeutic form of A. barbadensis, was used for this purpose. Three groups (one control and two test groups) of female Wistar albino rats with no prior births were studied. Group I was administered 25?mg (140?mg/kg) of A. barbadensis/day both orally and through gavage. A. barbadensis was contained in capsules with 500?mg of soybean oil; therefore Group II was administered 500?mg of soybean oil. Group III was the control group. All three groups were given normal food and water ad libitum. The substance had been administered for 20 days until birth. Ovaries were examined histologically. Vascular increase and the hyperemic form of ovary in the group administered A. barbadensis were notable. Decrease in primary follicle numbers, increase in secondary follicle numbers, and diminishment of secondary follicle diameters occurred in ovaries. The histological changes imply an angiogenesis effect of A. barbadensis and an effect like that of follicle-stimulating hormone in ovaries.enCC0 1.0 Universalinfo:eu-repo/semantics/openAccessAloe barbadensismorphologyrat ovaryArticle13976Q3139312