Abstract
We show that the linear ”2-generalized” birth and death processes (i.e. the processes defined from two death rates and
one birth rate) could be generated by the 2-orthogonal polynomials sets. In particular, we give a characterization of these
processes when their related 2-orthogonal polynomials are Sheffer-Meixner type. Also, we show that in one particular case,
it is possible to give an integral representation of the measures of orthogonality. In the general case, we give the integral
equations satisfied by the measures of orthogonality.