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dc.contributor.authorŞahin, Bahar
dc.contributor.authorSayın, Sercan
dc.contributor.authorÇelik, Arzu
dc.date.accessioned2020-08-28T07:31:56Z
dc.date.available2020-08-28T07:31:56Z
dc.date.issued2014en_US
dc.identifier.citationŞahin, B., Sayın, S. ve Çelik, A. (2014). Insulin pathway related salt inducible kinases in fruit fly retina development. Frontiers in Medical Sciences: Diabetes, Cancer and Their Connection / Tıpta Yenilikler: Diyabet, Kanser ve İlişkileri, Maltepe Üniversitesi. s. 89.en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/5985
dc.description.abstractSalt inducible kinases (SIKs) are Ser/Thr kinases members of AMPK-RK family. Upon regulation by glucagon induced PKA signal, SIKs regulate IRS-1, CRTC activity, and in turn CREB. Via the insulin induced Akt, SIKs are known to inhibit CREB and CRTC. Besides the long known role in insulin pathway, SIKs are target of a master tumor suppressor kinase Lkb-1; which is supported by many instances showing SIKs involvement in cancer progression.en_US
dc.language.isoengen_US
dc.publisherMaltepe Üniversitesien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsCC0 1.0 Universal*
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.titleInsulin pathway related salt inducible kinases in fruit fly retina developmenten_US
dc.typeconferenceObjecten_US
dc.relation.journalFrontiers in Medical Sciences: Diabetes, Cancer and Their Connection / Tıpta Yenilikler: Diyabet, Kanser ve İlişkilerien_US
dc.contributor.departmentMaltepe Üniversitesi, Tıp Fakültesien_US
dc.identifier.startpage89en_US
dc.identifier.endpage90en_US
dc.relation.publicationcategoryUluslararası Konferans Öğesi - Başka Kurum Yazarıen_US


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