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dc.contributor.authorYılmaz, T.
dc.contributor.authorAkman, M.
dc.contributor.authorTutluoğlu, Bülent
dc.contributor.authorAfrasyap, Lale
dc.contributor.authorGöylüsün, Veli
dc.contributor.authorÇelik, N.
dc.date.accessioned2020-10-06T13:14:58Z
dc.date.available2020-10-06T13:14:58Z
dc.date.issued1999en_US
dc.identifier.citationYilmaz, T., Akman, M., Tutluoğlu, B., Afrasyap, L., Göylüsün, V., ve Çelik, N. (1999). Plasma thrombomodulin levels in lung cancer patients. Panminerva medica, Edizioni Minerva Medica. 41(2), s.125-128 .en_US
dc.identifier.issn0031-0808 / 1827-1898
dc.identifier.urihttps://www.minervamedica.it/en/journals/panminerva-medica/article.php?cod=R41Y1999N02A0125
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6486
dc.description.abstractBACKGROUND: Thrombomodulin (TM) is a glycoprotein and besides its anticoagulant property it is accepted as an onco developmental antigen. Considering these properties we hypothesised that active TMB might have a role in cancer cell behaviour. METHODS: We measured serum TMB levels by the enzyme immunoassay method in 40 patients with lung cancer and 20 healthy subjects. RESULTS: TMB levels were found as 54.6 +/- 11.5 in controls and 60.9 +/- 31.2 ng/ml in lung cancer patients TM levels were 59.4 +/- 24.2 ng/ml in 24 epidermoid carcinoma patients, 65 +/- 50.2 ng/ml in 10 small cell carcinoma patients and 60 +/- 18.4 ng/ml in 6 adenocarcinoma patients. Patients with stage 4 and distant metastasis had a value of 65 +/- 33.9 ng/ml. No significant differences were found between healthy subjects and cancer patients. Also the differences between 3 groups of patients were insignificant. CONCLUSIONS: It was concluded that serum TMB levels could not be accepted as a tumour marker in lung cancer patients.en_US
dc.language.isoengen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titlePlasma thrombomodulin levels in lung cancer patientsen_US
dc.typearticleen_US
dc.relation.journalPanminerva Medicaen_US
dc.contributor.departmentMaltepe Üniversitesi, Tıp Fakültesien_US
dc.identifier.volume41en_US
dc.identifier.issue2en_US
dc.identifier.startpage125en_US
dc.identifier.endpage128en_US
dc.relation.publicationcategoryUluslararası Editör Denetimli Dergide Makaleen_US


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