Mortality-lowering effect of systemic corticosteroid therapy in severe tetanus
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CitationPaydaş, S., Akoğlu, T.F., Akkız, H., Özer, F. L. ve Burgut, H. R. (1988). Mortality-lowering effect of systemic corticosteroid therapy in severe tetanus. Clinical Therapeutics. 10(3), s. 276-280.
In a double-blind therapeutic trial, 32 patients suffering from severe tetanus were given prednisolone and 31 a placebo in addition to standard treatment. Mortality was lower in the prednisolone-treated group (31%) than in the placebo-treated group (55%). The women had more severe symptoms and a higher mortality than the men. The results suggest that the addition of a corticosteroid to standard treatment will lower mortality in tetanus, although meticulous nursing care is still the most important factor in treatment.
- Makale Koleksiyonu