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Allergic reaction due to the use of infliximab / Infliksimab kullanımına bağlı gelişen alerjik reaksiyon
(Maltepe Üniversitesi, 2022) Akça, Hatice Şeyma; Atik, Dilek; Köse, Fulya; Akça, Hanife Merve
In our case report, we aimed to describe a patient who was diagnosed with ankylosing spondylitis and developed anaphylactoid reaction after receiving infliximab treatment for the second time. Case Report A 21-year-old female patient presented to the emergency department with an allergic reaction after intravenous infliximab administration. It was learned that he received the treatment for the second time. It was observed that the general condition of the patient was moderate-poor, GCS:15, swelling of the tongue and lips and difficulty in breathing. We were informed that he had ankylosing spondylitis and familial Mediterranean fever in his history and that he was using prednol. In laboratory examinations, WBC was 31.26 KµL. The patient was monitored in the emergency department. Adrenaline, prednol and avil treatment was given. About 2 hours later, the patient's clinical and vital signs improved. After 12 hours of emergency follow-up, he was discharged with recommendations. Conclusion Infiximab, which is preferred in autoimmune diseases, should be applied carefully in terms of allergic reactions and close follow-up should be planned, even if no side effects are observed in the first application.