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    The efficacy of topical vitamin A in allergic conjunctivitis - case control research / Allerjik konjonktivitte topikal A vitaminin etkinliği- olgu kontrol araştırması
    (T.C. Maltepe Üniversitesi, 2024) Erdoğan, Hakika; Akingöl, Ziya; Taş, Kardelen
    Aim: The aim of this study is to evaluate the efficacy of topical vitamin A ointment (retinol palmitate, 250 IU/g) on the comfort of for the patients with symptomatic allergic conjunctivitis and dry eye. Material and Methods: 93 patients with seasonal and perennial allergic conjunctivitis were enrolled in this study. We prescribed topical vitamin A ointment and the classic ocular allergy treatment to 47 and classic ocular allergy treatment only to 46 (control group) patients, respectively. Patients’ ocular allergy and dry eye signs and symptoms were compared before and after the treatment in each group. Results: The topical vitamin A treatment and control groups led to significant improvement in the ocular examination in terms of ocular surface disease index (OSDI) scores and breakup time (BUT) values, but the results were comparatively better in the vitamin A group. We observed the results of the Oxford scheme for the corneal surface condition, and the main symptoms and the other findings of ocular allergy had improved in both the groups after the treatment, without significant differences between the groups. Conclusion: Our findings suggest that the adjunct treatment with topical vitamin A is effective for allergic conjunctivitis accompanied by dry eye symptoms.