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  • Küçük Resim Yok
    Yayın
    Lacrimal gland adenoid cystic carcinoma treated with intraarterial chemotherapy [İntraarteriyel kemoterapi ile tedavi edilen lakrimal gland adenoid kistik karsinomu olgusu]
    (2009) Karagöz B.; Bilgi O.; Duman C.; Başekim Ç.; Kandemir E.G.; Haholu A.; Özgün A.; Türken O.
    Adenoid cystic carcinoma is a malignant tumor of glandular tissue and progresses with local relapse and distant metastasis. In this report, we present a case of lacrimal gland adenoid cystic carcinoma who treated by multimodal approach with intraarterial chemotherapy. A 32-year-old woman was diagnosed with adenoid cystic carcinoma (solid variant) of the left lacrimal gland. Neoadjuvant intraarterial cisplatin, intravenous doxorubicin, and orbital exenteration were performed. The patient was followed for 32 months without relapse. Achievement of long-time survival for this disease supports studies that show benefit of intraarterial chemotherapy.
  • Küçük Resim Yok
    Yayın
    The Prognostic significance of comorbidity and relation of comorbidity with the other prognostic factors in patients with non small cell lung cancer [Küçük hücreli dişi akciger kanserinde komorbiditenin prognostik önemi ve diger prognostik faktörlerle i·lişkisi]
    (UHOD - Uluslararasi Hematoloji Onkoloji Dergisi, 2009) Özgün M.A.; Karagöz B.; Bilgi O.; Kandemir E.G.; Türken O.
    Comorbidities often be encountered in lung cancer patients. However, the relationship between lung cancer and comorbidity has not been investigated sufficiently yet. In this study, the prevelance of comorbidity in 358 patients with non small cell lung cancer diagnosed in Gülhane Military Medical Academy Haydarpasa Training Hospital was reviewed and its association with other known prognostic factors and impact of comorbidity on the prognosis was investigated. Comorbidity was significantly correlated with age, disease stage and performance status (p= 0.0001). There was no association of comorbidity grade with sex and histopathological type (p= 0.9, p= 0.5). Univariate analysis demonstrated significant associations between overall survival and comorbidity, as well as, age, disease stage, performans status and histopathological type (p= 0.00001). In multivariate analysis, high comorbidity grade, as independent from the other prognostic factors, influences overall survial negatively (p= 0.0001). As a result, it was found that comorbidity is an independent poor prognostic factor in patients with non small cell lung cancer.