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Yayın Islet inflammation, a causal link between diabetes and pancreatic cancer? / GLP-1 based therapy and the exocrine pancreas, accelerated dysplasia and cancer?(Maltepe Üniversitesi, 2014) Butler, PeterType 2 diabetes (T2DM) is characterized hyperglycemia due to impaired insulin secretion and a deficit of pancreatic beta cells in the setting of insulin resistance.