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Fertility following spinal cord injury
(ASRM, 2006) Cıncık, Mehmet; Akar, M. Erman; Bedir, S.; Selam, Belgin; Coban, H.; Ergür, A.R.
OBJECTIVE: To investigate the fertility of patients with spinal cord injuries (SCI) and their partners. DESIGN: Retrospective study. MATERIALS AND METHODS: Between April 2004 and April 2006, electroejaculation method was used to procure semen from 12 patients with anejaculation in 14 cycles. Sperm quality of the ejaculate was evaluated. All patients received concomitant pituitary down regulation with GnRH-agonist (Lupron, 0.1 mg sc) beginning in the midluteal phase of the preceding cycle. GnRH agonist was continued until the day of the HCG injection. Dose of recombinant FSH was individually adjusted every 1-3 days thereafter based on the results of serum E2 determinations. Routine IVF /ICSI procedures were performed. Oocytes were retrieved 34 hours after hCG injection. RESULTS: Semen was retrieved in all of the IVF/ICSI cycles. Embryo transfer was cancelled in three cycles because there was no fertilization. Mean age of the male patients was 28.4 6.1 (range 22-31). Mean number of grade 1 embryos on day 3 were 3.4 2 (range 1-10). Pregnancy rate per cycle was 21%. CONCLUSION: Semen for fertility purposes can be effectively obtained in patients with anejaculation using electroejaculation. Research may be focused on increasing sperm quality for these patients during assisted reproductive techniques.