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Yayın Assessment of interventricular septal motion using colour tissue Doppler imaging in adult patients with atrial septal defect(Sage Journals, 2004) Kardeşoğlu, Ejder; Cebeci, Bekir Sıtkı; Çelik, T.; Dinçtürk, Mehmet; Demiralp, E.We aimed to characterize changes in interventricular septum (IVS) motion and any relationship between them and the pulmonary-to-systemic flow ratio (Qp/Qs) in adult patients with atrial septal defect (ASD). Patients and controls were studied using colour tissue Doppler imaging (TDI). The septum length (SL) and distance from the colour change point (CCP) on the IVS to the aortic valve (the CCP distance) were measured on parasternal long axis views. Values normalized for body surface area, and the CCP distance to SL ratio, were calculated. Qp/Qs values were correlated with CCP distance, normalized CCP distance and CCP distance: SL ratio. Statistically significant differences in CCP distance, normalized CCP distance and CCP distance: SL ratio were found between the two groups. In the ASD group, there was no correlation between Qp/Qs and the echocardiographic measurements. The point between the motions in two different directions from the IVS shifted toward the apex in ASD patients compared with controls, and may be a mechanism involved in paradoxical septal motion.Yayın A case report: a rare form of right ventricular fibroma(Kartal Koşuyolu Yüksek İhtisas EAH, 2003) Cebeci, Bekir Sıtkı; Çelik, T.; Kardeşoğlu, Ejder; Işılak, Zafer; Dinçtürk, M.; Süngün, Mutasım; Demiralp, E.A Case Report: A Rare Form of Right Ventricular FibromaYayın Role of homocysteine for thromboembolic complication in patients with non-valvular atrial fibrilation(Wolters Kl, 2002) Yiğiner, Ömer; Cebeci, Bekir Sıtkı; Kardeşoğlu, Ejder; Demiralp, E.; Dinçtürk, MehmetThromboembolism is the most important complication in patients with atrial fibrilation (AF). Homocysteine is a toxic amino acid that has been recently accepted as a risk factor for atherosclerosis and stroke. The aim of the present study is to show whether there is a relation between hyperhomocysteinemia and thromboembolic complications in patients with non-valvular AF. We admitted 38 patients with non-valvular AF. The patients were divided into two groups: group A (n = 20; mean age, 75.7 +/- 10.4 years; three males/17 females), and group B (n = 18; mean age, 68.0 +/- 10.6 years; 11 males/seven females). While group A consisted of the patients with AF and stroke, group B was composed of the patients with AF but without stroke. The patients having sinus rhythm (15 subjects) were used as the reference group to obtain the cut-off value. Homocysteine was measured by the immunoassay method. The means of the homocysteine levels were 12.4 +/- 3.3 micromol/l in group A, 8.3 +/- 2.3 micromol/l in group B and 9.3 +/- 1.8 micromol/l in the reference group. The cut-off value was 10.6 micromol/l. Group A had a statistically higher homocysteine level than not only group B, but also the reference group (P < 0.05). While 60% of group A (n = 12) had the elevated homocysteine level, the rate was only 22% for group B (n = 4). In conclusion, hyperhomocysteinemia may be one of the explanations for the increased rate of thromboembolic complications in older patients with AF.Yayın Wellens' syndrome: a case report(Sage Journals, 2003) Kardeşoğlu, Ejder; Çelik, T.; Cebeci, Bekir Sıtkı; Dinçtürk, Mehmet; Demiralp, E.The pattern of clinical findings and electrocardiography (ECG) changes known as Wellens' syndrome is associated with significant stenosis of the proximal left anterior descending coronary artery. Cases can be classified according to the ECG pattern into type 1 (biphasic T waves) or type 2 (deeply inverted T waves, especially in leads V2 and V3). We present here an unusual case of Wellens' syndrome in which the ECG pattern changed from type 2 to type 1 during observation, and in which the coronary lesion was in the middle rather than the proximal part of the left anterior descending artery.