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    Can Neutrophil Lymphocyte Ratio Predict the Likelihood of Suicide in Patients with Major Depression?
    (CUREUS INC, 2018) Meydaneri, Gozde Gundogdu; Meydaneri, Sertac
    Background Neutrophil lymphocyte rate (NLR), platelet lymphocyte rate (PLR), and systemic immune inflammatory index (SIII) are rates obtained from hemogram parameters, and they are biomarkers used for the diagnoses of many diseases and their severity, and prediction of disease. In addition to the NLR, PLR, and SIII, platelets, plateletcrit (PCT), and platelet distribution width (PDW), which are platelet indices, are also investigated as biomarkers in many diseases. There are limited studies on the use of hemogram derivates (NLR, PLR, and SIII) in the diagnosis and severity determination of psychiatric disorders. Objectives In this study, we aimed to investigate the effect of biomarkers and the proportions of NLR, PLR, and SIII, which are obtained from hemogram parameters, to distinguish or predict the patients with major depression who are likely to commit suicide. Materials and methods In this retrospective study, the files of patients referred to an educational research emergency and psychiatric outpatient clinic between June 2017 and December 2017 were evaluated. Patients who had been referred to the emergency polyclinic because of suicide attempts and those with major depression diagnosed at a psychiatric clinic were evaluated in this study. All hemogram evaluations were performed using the Sysmex XT-20001 Automated Hematology Analyzer (GMI, MN, USA). Results Twenty-seven suicide patients and 26 major depression groups meeting the study acceptance criteria were included in the evaluation. Of these patients, 40 were female and 13 were male. There was no difference between the groups in terms of age, body mass index, and complete blood count (CBC) parameters such as white blood cell (WBC), neutrophil count, lymphocyte count, eosinophil count, monocyte count, platelet indices, and NLR, PLR, SIII, which were obtained from the hemogram. Conclusion We found that the neutrophil to lymphocyte ratio and other biomarkers obtained from hemograms were higher in patients with major depression than those who had suicide attempts, but we found that this was not statistically significant.
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    Evaluation of analgesic regimens in total knee arthroplasty, retrospective study
    (KARE PUBL, 2017) Tulgar, Serkan; Selvi, Onur; Senturk, Ozgur; Serifsoy, Talat Ercan; Sanel, Selim; Meydaneri, Sertac
    OBJECTIVE: Analgesic therapies have an immense role in early rehabilitation period after total knee arthroplasty (TKA) and multimodal approaches should be considered as the first choice of treatment. In this retrospective study, the aim was to evaluate the effectiveness of multimodal analgesic therapies for TKA, including femoral nerve block (FNB) and patient controlled analgesia (PCA). METHODS: The data of 79 patients who underwent TKA between January and December 2016 were retrospectively evaluated. In all, 63 patients met the inclusion criteria. Hemodynamic records and Visual Analogue Scale (VAS) pain scores for postoperative 0, 2, 4, 6, 9, and 12 hours were evaluated and patients were separated into 3 groups. Group 1: FNB with 0.25% bupivacaine, Group 2: FNB with 0.166% bupivacaine, and Group 3: No FNB. RESULTS: The average age of the patients was 64.3 +/- 14.9 years and average body mass index (BMI) was 32.5 +/- 5.3 kg/m(2). There was no statistical difference between groups in age, gender, American Society of Anesthesiologists (ASA) classification of physical health scores, BMI, or anesthesia type (p<0.05). When VAS scores at postoperative time intervals were compared, there was a statistically significant difference between Group 1 and Group 2 (p>0.05). When difference between Groups 1 and 3 and Groups 2 and 3 were compared, the difference was statistically significant for VAS 0 (p>0.05). Additional analgesic use was highest in Group 3. CONCLUSION: This study demonstrated that FNB significantly decreases postoperative pain intensity and additional analgesia requirement in patients undergoing TKA. A concentration of 0.166% bupivacaine is as effective as a concentration of 0.25% when used as part of a multimodal analgesia regimen in TKA.
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    Fluoroscopic visualization of 4+5 extensor compartmental arteries in Kienbock's Disease
    (Kashan Univ Medical Sciences, 2023) Coşkun, Tamer; Meydaneri, Sertac; Kurkcuoğlu, Tolga
    Background: Many surgical treatment methods have been presented for Kienbock's disease. The most current treatment method is the surgical procedure with 4+5 extensor compartmental artery (ECA) bone graft. However, the graft harvest site is very close to the radioulnar and radiocarpal joints. Objectives: This study aimed at determining the efficacy of intraoperative fluoroscopy evaluation of 4+5 ECA. Methods: Intraoperative fluoroscopic visualization of the 4+5 ECA may facilitate the surgical procedure. Patients with lunate avascular necrosis at stage II-IIIA according to Lichtman classification who underwent 4+5 ECA bone graft were included in the study. A total of 13 patients (3 females, 10 males) participated in the study. Results: The mean follow-up period of the patients was 15 months. In all patients, 4+5 ECA localizations were determined fluoroscopically. None of the patients experienced complications related to graft harvest. Conclusion: Locating the intraoperative fluoroscopic 4+5 ECA may make the surgical procedure safer.