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Yayın Are Hounsfield densities of ureteral stones a predictive factor for effectiveness of extracorporeal shock wave lithotripsy?(E-CENTURY PUBLISHING CORP, 2014) Cakiroglu, Basri; Eyyupoglu, S. Erkan; Tas, Tuncay; Balci, M. B. Can; Hazar, Ismet; Aksoy, S. Hilmi; Sinanoglu, OrhunExtracorporeal Shock Wave Lithotripsy (SWL) has long been used successfully to dissolve ureteral stones. We researched whether Hounsfield values of ureteral stones is a factor that affects the success of SWL. Methods: Data from 144 patients who had diagnoses of ureteral stones and underwent SWL, were retrospectively reviewed between January 2011 and December 2012. Urinary tomography of patients was processed and classified into 3 groups by Hounsfield units (Group 1, < 500 HU; Group 2, 500-1000 HU; and Group 3, > 1000 HU) and 2 groups by stone size (Group A; < 1 cm, Group B; > 1 cm). SWL success was analyzed for both of these group types. Failure was defined as any fragments of the stone that remained within the ureter. Results were analyzed by evaluating the predictive factors in both groups. Results: The study included 144 patients (100 men, 44 women) who fit the inclusion criteria. In Hounsfield unit Group 1 (12 women and 44 men), the mean age was 37.2 +/- 13.2, stone size was 8.5 +/- 2.5 mm, number of shocks was 3240 +/- 1414 (1200-7500) and number of treatments was 1.4 +/- 0.6. In Group 2 (26 women and 32 men), the mean age was 33.6 +/- 7.6, stone size was 9.6 +/- 3.1 mm, process number was 3375 +/- 2103 (1200-8750) and shock amount was 1.6 +/- 0.8. In Group 3 (6 women and 24 men), the mean age was 42.2 +/- 13.6, stone size was 11.7 +/- 3.0 mm, number of shocks was 4513 +/- 2458 (1300-8700) and number of treatments was 2.1 +/- 1.2. In size Group 1 (28 women and 74 men), the mean age was 35.8 +/- 10.6, stone size was 8.1 +/- 1.4 mm, process number was 3105 +/- 1604, shock amount was 1.4 +/- 0.5 and HU value was 580 +/- 297. In Group 2 (16 women and 26 men), the mean age was 39.9 +/- 14.2, stone size was 13.9 +/- 2.4 mm, number of shocks was 4722 +/- 2467, number of treatments was 2.3 +/- 1.1 and HU value was 912 +/- 270. Conclusion: Although stone density predicted the failure of SWL, size of the stone is more important criterion for successful lithotripsy of ureteral stones.Yayın The effect of inclined position on stone free rates in patients with lower caliceal stones during SWL session(PAGEPRESS PUBL, 2015) Cakiroglu, Basri; Sinanoglu, Orhun; Tas, Tuncay; Hazar, Ismet Aydin; Balci, Mustafa Bahadir CanObjective: To compare the outcomes of shock wave lithotripsy (SWL) combined with inclined position and SWL alone in patients with lower pole calyx stones. Methods: Seven hundred forty patients who underwent SWL treatment for lower pole renal stones with a total diameter of 2 cm or less were prospectively randomized into two groups. They were comparable in terms of age, sex, and stone diameters. Patients with lower calyceal stones (4-20 mm) were randomized to SWL (368 patients) or SWL with simultaneous inclination (372 patients) with 30o head down Trendelenburg position). Shock wave and session numbers were standardized according to stone size. Additional standardized shock waves were given to patients with stone fragments determined by kidney urinary bladder film and ultrasound at weeks 1, 4, 10. Results: The overall stone free rate (SFR) was 73% (268/368) in patients with SWL alone and 81% (300/372) in SWL with inclination at the end of 12th week (p = 0.015). No significant adverse events were noted in both treatment groups. Conclusion: Simultaneous inclination of patients during SWL session increase SFR in lower caliceal stones significantly compared to SWL treatment alone.Yayın The histology and the proapoptotic control in the ipsilateral and the contralateral testes following unilateral vasectomy(PAGEPRESS PUBL, 2015) Hazar, Aydin Ismet; Cakiroglu, Basri; Sakalli, Ertan; Balci, Mustafa Bahadir Can; Eyyupoglu, Erkan; Tas, Tuncay; Sinanoglu, Orhun; Tuzlali, Pinar; Cilesiz, Nusret CanObjective: The aim of this study was to enlighten both the testicular histology and the genetic aspects of the apoptotic process. Thus an experimental study was designed with a model of unilateral vasectomy. Methods: Twenty-two adult male rats were used and 4 main groups were formed. The first (A), the second (B), the third (C), and the fourth group (D) consisted of 4, 4, 4 and 10 rats respectively. Rats in group A had sham operation while rats in other groups (B, C, D) underwent left vasectomy operation including binding of ductus deferens with a 3/0 silk and cutting a minimum of 1 cm part while preserving the vascular structure under 9x magnification. Rats undergoing unilateral vasectomy were sacrificed at the 1st, 2nd and 8th weeks and their testicular structure and proapoptotic gene proteins were compared with that of the control group undergoing sham operation. Results: We found that vasectomy gradually caused destruction and both ipsilateral and contralateral testicles were affected showing initial apoptosis. Conclusion: The procedure causes destruction in the testicular structure by causing bilateral intratubular germ cell necrosis, unilateral obstruction, increase in the tubular pressure and processes that are aggravated by some probable autoimmune reactions.Yayın Monosymptomatic nocturnal enuresis caused by seasonal temperature changes(E-CENTURY PUBLISHING CORP, 2014) Tas, Tuncay; Cakiroglu, Basri; Hazar, Aydin Ismet; Balci, Mustafa Bahadir Can; Sinanoglu, Orhun; Nas, Yunus; Yilmazer, FazliBackground: Primary nocturnal enuresis is the most frequent urologic complaint among pediatric patients. Enuresis is believed to have a complex etiology involving genetic, somatic, and behavioral factors. We study the relationship between seasonal temperature changes effect and monosymptomatic nocturnal enuresis (MNE). Methods: Between 2011 and 2012, a total of 75 children with primary MNE selected from urology and pediatry clinics were included in this study. All of the children underwent physical examinations, urine analyses, urinary ultrasounds, and direct urinary graphs. We evaluated the enuresis ratio for the summer (the hot season from June to September) and winter (the cold season from December to March) months in nightly, weekly, and monthly intervals via prepared questionnaires. Results: Of the 75 study participants, 45 were boys (60%) and 30 were girls (40%). The age range was 6-16 years (mean 10.3 +/- 2.0 years). We observed a difference in the ratio of enuresis data between the summer and winter months in 29 males and 19 females, which totals 48 of the 75 MNE patients evaluated in this study. There was a statistically significant difference noted in monthly enuresis ratio in the summer and winter (p<0.0001). We observed a significant difference in quality of life, and this difference caused considerable emotional discomfort for the patients. Conclusion: In the winter months, the nightly, weekly, and monthly ratios are higher in children with MNE. This increase causes a decrease in the quality of life of these children.Yayın Penile Mondor's Disease Induced by Vigorous Sexual Activity: Two Cases, Two Different Approaches(ORTADOGU AD PRES & PUBL CO, 2012) Aydin, Memduh; Tas, Tuncay; Gursoy, Gokhan; Sinanoglu, Orhun; Balci, Mustafa Bahadir Can; Hazar, Aydin Ismet; Nuhoglu, BarisPenile Mondor's disease is a painless superficial induration due to thrombosis of penile superficial dorsal vein. Etiological factors for superficial dorsal penile vein thrombosis include trauma, vigorous sexual activity, pelvic tumors and a distended bladder. Doppler ultrasonographic evidence of thrombotic dorsal penile vein is diagnostic for penile Mondor's disease. Two cases with Mondor's disease of the penis due to brutal sexual intercourse are reported here. The first patient's thrombosis resolved spontaneously whereas in the second one anti-inflammatory and heparinoid agents were applied. The treatment should primarily be based on temporary sexual abstinence, and in case of no response treatment with non-steroid anti-inflammatory agents, local anticoagulants should be administered. Larger series are needed to determine whether initial observation is appropriate for all patients with penile Mondor's disease.
