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Yayın The impact of preventive programs on the reduction of mortality of malignant diseases in the republic of croatia(Maltepe Üniversitesi, 2019) Toma, Denis; Ilic, BorisINTRODUCTION: Malignant diseases are one of the leading health problems in the Republic of Croatia. According to the data of the Croatian Institute of Public Health, they take second place in the mortality rate with a share of 27.8%. In order to reduce the mortality and morbidity of the citizens of the Republic of Croatia, three national preventive programs have been designed and adopted. DISCUSSION: In the Republic of Croatia, five public health prevention programs are being implemented. Preventive program for early detection of breast cancer, cervical cancer and colon cancer. Since the onset of the prevention programs, the mortality in regard to breast cancer among women is about 50 patients annually (2%), in comparison to the year of 2000 when the program was not yet adopted, where 38.5% or 843 of the 2,187 patients died. In the period from 1990 – 2012, 11,643 women were diagnosed with cervical cancer and 4,894 of them had died. The number of new cases in 1990 was 391, while in 2012 it was 651. Between 1990 and 2012, the number of mortalities from cervical cancer was 4,894. We can observe that in the last decade the number of new discoveries women under this diagnosis is on a steady rise, while mortality stagnates. Colon cancer is the second in appearance and mortality of malignant neoplasms in both genders. This type of malignant disease in Croatia annually affects approximately 3,000 people of both genders, while about 2,000 people die as a result of it, which is a steady trend in recent years. The colon cancer is discovered in 3,229 patients in 2015 and in 2016, 2169 died of this disease, which is a four cause of death in Croatia. According to the data of the Croatian Institute of Public Health, 2,800 new cases with colon cancer occurred in 2000, while more than 1,500 died. By adopting the preventive programme the number of newly diagnosed cases has increased by 529. Mortality was also increased by 669, suggesting that colon cancer, despite the warning of the public, is revealed later in the final phase when it expands in lymphatic vessels, although mortality is growing slower than incidence. CONCLUSION: The number of newly discovered malignant neoplasia has been increased by the implementation of preventive programs, which resulted in an average decrease of 200 mortalities of all neoplasms (C00 to C97 MKB, without C44) due to the early onset of therapeutic procedures. Despite numerous media and public health campaigns, citizens ‘response is still insufficient and additional efforts are needed to increase citizens’ awareness of the importance of participating in prevention and early detection programs.