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    The effect of smoking on family functions
    (2022) Uslu, Dilek Nurlu; Arslan, İsmail; Uslu, Sadettin; Gülmez, Gülay; Demir, Şevin; Tekin, Oğuz
    Aim: Family is the most natural environment where people can meet their needs of love, compassion, affection and care for mental and physical health. In this study, we aim to investigate the relation between smoking and family functions. Material and Method: Ninety seven patients between 18-60 years age who were admitted to the Ankara Training and Research Hospital, live with at least one family member and agreed to participate in the study were included in this study. Cross-sectional, observational and analytic methods were applied. The recorded data of the participants were as follows: age, sex, occupation, marital status, education level, the family members whom living with, the status of smoking at home, chronic diseases and current medication. McMaster Model of Family Functioning (MMFF) and Fagerström Test for Nicotine Dependence (FTND) were used. Results: Statistically significant differences between MMFF scores of smoking patients in the subscales of “Roles” and “Affective Involvement” were found (p=0.004, p= 0.002, respectively). We have seen in the subscale of “Problem Solving” that single members were negatively affected (p=0.033). The negative effects of smoking were found to be decreasing by age in the “Communication” subscale (p=0.002). The “Roles” subscale was observed to be negatively disturbed in the group of smokers with chronic diseases(p=0,050). We also found that being single and having a chronic disease negatively affected “Affective Responsiveness” subscale (p=0.050, p=0.020, respectively). Conclusion: Smoking affects the family functions negatively. Thus, the fight against smoking might be thought to make a favorable effect on the family functions.
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    Propylthiouracil induced p-ANCA+ pyoderma gangrenosum: Case report and review of literature / Propiltiourasil ile indüklenen p-ANCA+ pyoderma gangrenozum: Olgu sunumu ve literatürün gözden geçirilmesi
    (Maltepe Üniversitesi, 2020) Uslu, Sadettin; Köken Avşar, Aydan; Karakas, Ali
    Propylthiouracil is a drug commonly used in patients with hyperthyroidism. Some patients with Graves using this drug may have a positive perinuclear antineutrophil cytoplasmic antibody (p-ANCA) associated with different forms of vasculitis and neutrophilic dermatoses. However, skin lesions such as maculopapular purpura, erythema, sensitive nodules, ulceration, vesiculobullous lesions, and livedo can be induced by antineutrophil cytoplasmic antibody (ANCA) -positive vasculitis. In these cases, the development of pyoderma gangrenosum (PG) is very rare. We aimed to present a concurrent development of pyoderma gangrenosum, p-ANCA positivity and inraalveolar hemorrhage in a patient who had been using PTU for a long time and to discuss the current literature with this presentation. We think that the baseline ANCA levels should be measured in all graves patients because of severe ANCA-related vasculitis in some patients during PTU therapy.