Comparative characteristics of morphological changes in the lungs in coronavirus disease (COVID-19) and influenza type A (H1N1)

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Tarih

2021

Dergi Başlığı

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Cilt Başlığı

Yayıncı

Maltepe Üniversitesi

Erişim Hakkı

info:eu-repo/semantics/openAccess

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Organizasyon Birimleri

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Özet

New COVID-19 infection and influenza A (H1N1) sometimes have a similar clinical picture. In both cases there is a respiratory disease, which can be mild and severe, and lead to death. Compare the COVID-19 and influenza A (H1N1), identifying common and different morphological changes in the lungs. Compare the COVID-19 and influenza A (H1N1), identifying common and different morphological changes in the lungs. The analysis of the results of 24 pathological autopsies of persons who died as a result of COVID-19 and influenza A (H1N1) on the basis of the pathological department of Ivano-Frankivsk Regional Clinical Hospital. The studied diseases has the main common morphological manifestation in the lungs - diffuse alveolar damage (DAD). In the case of COVID-19, the lung tissue is diffusely compacted and rather airless, the surface of the characteristic "lacquered" appearance, in section dark cherry or reddish-brown, with areas of atelectasis (dystelectasis), often large fuse hemorrhages, hemorrhagic infarcts of various sizes. Also characterized by multiple parietal and obstructive thrombi of the branches of the pulmonary arteries and veins of various calibers, foci of pneumosclerosis and / or signs of purulent pneumonia. Influenza A is manifested primarily by systemic toxicosis and capillarotoxicosis with a predominant lesion of the microvessels of the upper respiratory tract and lungs. People who die in the first week of the disease are macroscopically diagnosed with hemorrhagic tracheobronchitis, in the lungs plethora, edema, tightness, shortness of breath and hemorrhage. The morphological picture of the lungs in both COVID-19 and influenza A (H1N1) depends on the time of the disease. COVID-19 is characterized by interstitial pneumonia, vascular lesions of the microcirculatory channels with the development of blood clots and thromboembolism. Influenza type A (H1N1) is characterized by: high mortality during the first week of the disease, which is probably justified by systemic toxicosis, the presence of hemorrhagic tracheobronchitis, hemorrhagic bronchopneumonia.

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Kaynak

International Faculty of Medical Sciences and Nursing(MEDNS) Student Congress

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Künye

Vikhnesh, S.K., Solomia, P. ve Maurya, A. (2021). Comparative characteristics of morphological changes in the lungs in coronavirus disease (COVID-19) and influenza type A (H1N1). International Faculty of Medical Sciences and Nursing(MEDNS) Student Congress, Maltepe Üniversitesi. s. 40-41.