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Yayın The effect of exosomes derived from different breast cancer cell lines on mesenchymal stem cells and stromal cells(Maltepe Üniversitesi, 2014) Subaşı, Cansu; Duruksu, Gökhan; Karaöz, ErdalProliferation and expansion of cancer cells exhibit different characters compared to the stromal cells. These cells have the capacity for unlimited proliferation, tumor formation and migration into tissues and organs under the influenceof a variety of factors.Yayın The effects of Cd4+ and Cd8+ T cells on human B cells derived from Type 1 diabetic patients and healthy individuals(Maltepe Üniversitesi, 2014) Yusufoğlu, Sema; Aksoy, Ayça; İnci, Çiğdem; Sağlam, Özlem; Erman, Gülay; Karaöz, ErdalWorldwide, millions of people are living with diabetes, and this number is increasing daily. Type-1 diabetes, also called as "Juvernil diabetes mellitus or IDDM (Insulin Dependent Diabetes Mellitus), is based on the insulin hormone deficiency, and mostly diagnosed in children and teenagers.Yayın Immunosuppresive and anti-apoptotic properties of pancreatic islet derived stem cells(Maltepe Üniversitesi, 2014) Karaöz, ErdalSeveral studies have been reported on the in vitro expansion of stem cells from pancreatic islet ( PI-SCs) cultures and on the differentiation of these SCs into multi-lineage cells.Yayın Response of pancreatic beta cells to extracellular matrix proteins: viability, proliferation and functionality(Maltepe Üniversitesi, 2014) İnci, Çiğdem; Duruksu, Gökan; Karaöz, ErdalDiabetes mellitus is defined as a metabolic disorder resulting from the deterioration of glucose and fat metabolism of body. Type-1 diabetes develops by formation of autoimmune response against beta cells.Yayın Studying the efficiency of subcutaneous transplantation of bone marrow-derived mesenchymal stem cell sheet with 3D islet tissue(Maltepe Üniversitesi, 2014) Öncel Duman, Büşra; Eker Sarıboyacı, Ayla; Karaöz, ErdalLatest approach of tissue regenerating is to construct cell layers instead of singe cells in order to mimic in vivo environment better. Temperature-responsive polymers are covalently grafted onto the dishes, allowing various types of cells to adhere and proliferate at 37 C.
