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    Effects of hypoxia on Hif-1 protein factors and in the formation of angiogenesis
    (Maltepe Üniversitesi, 2018) Karadeniz, Bilge; Turan, Aslıhan; Karakuş, Ayşe Selin; Çakıl, Yaprak Dönmez; Öztopcu, Aslı; Öztürk, Şenay; Özünal, Zeynep Güneş
    Cancer cells differ from normal cells in terms of unregulated, rapid and continuous segregation and reproduction. Therefore, cancer cells can create tumor tissue in time where it first occur. As the tumor tissue grows, the amount of oxygen in the tissue starts to decrease. A hypoxic environment started to form in the tissue by lowering the amount of oxygen and this hypoxic eovironment effects the regulation of gene expression.