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Yayın Croatian adolescents’ knowledge on menstrual cycle and hygiene(Maltepe Üniversitesi, 2019) Valicevic, Gloria; Ilic, Boris; Zupanic, MaraINTRODUCTION: In the Republic of Croatia, at the end of the standardized and mandatory primary education that lasts 8 years, students decide in which direction they want to continue their education. There is a significant difference in regard to the amount of hours and classes related to Biology and other life science subjects, between medical secondary schools and nonmedical secondary schools. AIM: The aim of this paper was to compare the knowledge of adolescents about the menstrual cycle and hygiene, as well as to determine if there are differences in the knowledge of students in medical schools and other non-medical schools. METHODOLOGY: 120 female participants took part in the research, with an average age of 17 years. Participants were divided into two groups, with 84 adolescents from medical secondary schools and 36 adolescents from non-medical secondary schools. An anonymous questionnaire was used, that consisted of several parts – sociodemographic data, questions regarding emotions and readiness during the first menstrual cycle, overall knowledge about the menstrual cycle, education on the menstrual cycle. The data were analyzed using statistical methods and content analysis and presented as percentage values. The study was approved by the Ethical Committee of the school where the research was conducted. RESULTS: The average age of the examinees getting their first menstruation was 12 years. 65% of the participants state that they find it easy to talk to their mother about menstruation. 43% of the participants said that during the menstruation they felt unpleasant. Adolescents that attended medical secondary school more often gave the correct answer to the question about the duration of the menstrual cycle (Chi-square, p <.001). Medical secondary school students also more often gave the correct answer to the question when the ovulation occurs (p <.001). CONCLUSION: Significant differences were found in knowledge between students from medical secondary school and non-medical vocational school. Students of medical secondary school had more knowledge about menstrual cycle and hygiene. Raising the educational level of adolescents, ensuring the availability of reliable information as well as implementing the education on menstrual cycle and hygiene at the early adolescence will significantly impact the prevention of unwanted pregnancies, decrease in fear connected to the menstruation, along with prevention of sexually transmitted diseases. Keywords: menstrual cycle, menstrual hygiene, adolescent, knowledge.