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    Endovascular management of acute complicated type B aortic dissection [Akut komplike tip B aortik diseksiyonlarin endovasküler tedavisi]
    (2011) Numan F.; Gülşen F.; Arbatli H.; Yilmaz O.; Solak S.
    Aortic dissection represents the most common aortic pathology requiring emergency treatment, and is still associated with a high mortality. In uncomplicated acute type B dissections, medical therapy results in an in-hospital survival rate of 90%, while complicated acute type B dissection is still a challenging clinical entity. Advances in endovascular technology have provided new treatment options. Endovascular treatment offers an exciting potential in the management of complicated type B dissection through sealing of the intimal tear area. Endovascular approach offers a less invasive mode of therapy for this high-risk group of patients by eliminating the necessity for thoracotomy, single-lung ventilation, and aortic crossclamping. This article aims to review the basics and results of endovascular treatment in the literature in patients with acute complicated type B aortic dissection.
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    Murmur after myocardial infarction: Is always a post myocardial infarction ventricular Septal defect: Case report
    (2013) Yilmaz O.; Ardal H.; Arbatli H.; Soybir N.; Sönmez B.
    ABS TRACT Symptoms of acute left heart failure dominate in both ventricular septal defects occurring after transmural myocardial infarctions (post MI VSD) and rupture of a sinus Valsalva aneurysm (SVA), which may pose a difficulty in differential diagnosis. Ruptured SVA mandate prompt and urgent surgical correction. Also patients with post myocardial infarction VSD should undergo emergent surgery. The success of the surgery in both situations depends on the prompt medical stabilization of the patient and the prevention of cardiogenic shock. Implantation of an intraaortic balloon pump would have been life-saving in case of a post-MI VSD, but would have increased the aorto-right atrial shunt and aggravate the left heart failure in a ruptured SVA, thus may have even led to the loss of the patient. Simultaneous coronary artery disease and ruptured SVA is extraordinarily rare. We present here, a case of ruptured SVA with concomitant coronary artery disease, who had an MI two weeks before. Copyright © 2013 by Türkiye Klinik leri.
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    Nitric oxide, endothelin-1, and superoxide production in arterial bypass grafts
    (2006) Aksungar F.B.; Moini H.; Unal M.; Yilmaz O.; Sonmez B.; Bilsel S.
    In this study, basal and thrombin-stimulated release of nitric oxide and endothelin-1 in the internal mammary artery and the radial artery were measured, together with superoxide radicals generated after anoxia and reoxygenation. Arterial segments were obtained from patients undergoing coronary bypass operations. Quantification of nitric oxide was performed by measuring the stable oxidation products of nitric oxide. Endothelin levels were measured by an enzyme immunoassay kit, and the superoxides were measured by lucigenin-enhanced chemiluminescence. Basal and stimulated release of nitric oxide from the internal mammary artery is significantly higher than that in the radial artery. On the other hand, basal release of endothelin-1 is less in the internal mammary artery than in the radial artery, but similar after stimulation. In our study, the quantity of superoxide radicals produced by the internal mammary artery was greater than that produced by the radial artery. Our results show that there are differences between these 2 arteries in regard to production of nitric oxide, endothelin-1, and superoxide radicals. These differences may have a role in the process of atherogenesis and may contribute to long-term patency of arterial bypass grafts. These results may also explain the mechanism of radial artery graft spasm in coronary artery surgery and may constitute a basis for future pharmacological and clinical improvements for successful surgical application. © 2006 by the Texas Heart® Institute.