Protective effects of L-arginine on rat terminal ileum subjected to ischemia/reperfusion
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WoltersKluwer
Erişim Hakkı
CC0 1.0 Universal
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
Studies have shown that nitric oxide (NO) may play a major role in sustaining mucosal integrity; however, NO has been also implicated in the pathogenesis of ischemia/reperfusion (I/R)–related tissue injury. We investigated the effects of L-arginine and NG-nitro L-arginine methyl ester (L-NAME) on the acetylcholine-induced contractile response of ileum and the levels of malondialdehyde (MDA) and reduced glutathione (GSH). Histopathological changes were also evaluated in ileal preparations.
Açıklama
Anahtar Kelimeler
Contractile activity, Ileum, Ischemia and reperfusion, Nitric oxide
Kaynak
WoS Q Değeri
Scopus Q Değeri
Q1
Cilt
46
Sayı
1
Künye
Sayan, H., Ozacmak, V.H., Altaner, S., Aktas, R.G. ve Arslan, S.O. (2008). Protective effects of L-arginine on rat terminal ileum subjected to ischemia/reperfusion. Journal of Pediatric Gastroenterology and Nutrition, WoltersKluwer. 46(1), s. 29-35.