Effect of postoperative administration of hyaluronic acid/trehalose drop on corneal healing after phacoemulsification surgery

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dc.authorid0000-0001-7749-2814en_US
dc.authorid0000-0002-0348-398Xen_US
dc.date.accessioned2024-07-12T21:02:09Z
dc.date.available2024-07-12T21:02:09Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractThis study aimed to evaluate the efficacy of hyaluronic acid/trehalose drop for corneal epithelial and stromal healing after phacoemulsification surgery. It is a retrospective randomized comparative study. The patients had phacoemulsification surgery divided into two groups. These patients received either a mixture of sodium hyaluronate and Trehalose (Group 1) or sodium hyaluronate 0.15% (Group 2) postoperatively. The effect on corneal epithelial and stromal healing was evaluated using Oxford staining and the vertical scar length measured by optical coherence tomography. Preoperative and post-operative findings for Oxford staining, Schirmer’s test, tear film break-uptime, and ocular surface disease index scores were also evaluated. The correlation between scar length and tear film parameters was examined. The effect of Trehalose on the epithelial healing and stromal scar formation was assessed. Group 1 and 2 each had 30 eyes. The two groups were similar according to age and sex distribution. In terms of epithelial healing, it was faster in the trehalose group, although there was no statistical difference between the two groups. The length of the stromal scar was not significantly different between groups. However, a smaller scar formation was observed in group 1 compared to those in group 2 at both one week and one month postoperatively. There was also no significant difference between the groups in tear film parameters. The stromal scar length was correlated with the Schirmer test on the 15th day. Although it was not statistically significant, the hyaluronic acid/trehalose may affect epithelial healing and stromal scar formation positively after phacoemulsification surgery. Larger and longer studies are needed.en_US
dc.identifier.citationErdoğan, H. ve Muhsinoğlu, O. (2021). Effect of postoperative administration of hyaluronic acid/trehalose drop on corneal healing after phacoemulsification surgery. Black Sea Journal of Health Science, Cem Tırınk. 4(1), s. 17-21.en_US
dc.identifier.endpage21en_US
dc.identifier.issue1en_US
dc.identifier.startpage17en_US
dc.identifier.urihttps://dergipark.org.tr/tr/pub/bshealthscience/issue/56779/788064
dc.identifier.uri2619 – 9041
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3586
dc.identifier.volume4en_US
dc.institutionauthorErdoğan, Hakika
dc.institutionauthorMuhsinoğlu, Orkun
dc.language.isoenen_US
dc.publisherCem Tırınken_US
dc.relation.ispartofBlack Sea Journal of Health Scienceen_US
dc.relation.isversionof10.34248/bshealthscience.788064en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.snmzKY00431
dc.subjectHyaluronic acid/trehaloseen_US
dc.subjectPhacoemulsification surgeryen_US
dc.subjectDry eyeen_US
dc.subjectWound healingen_US
dc.subjectClear corneal incisionen_US
dc.titleEffect of postoperative administration of hyaluronic acid/trehalose drop on corneal healing after phacoemulsification surgeryen_US
dc.typeArticle
dspace.entity.typePublication

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