Diagnostic value of ischaemia-modified albumin for predicting myocardial ischaemia during myocardial perfusion scintigraphy

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dc.authorid0000-0002-5634-1280en_US
dc.authorid0000-0003-1407-5313en_US
dc.contributor.authorÖzmen, Namık
dc.contributor.authorCanbolat, N.
dc.contributor.authorAparcı, Mustafa
dc.contributor.authorKardeşoğlu, Ejder
dc.contributor.authorNarin, Y.
dc.contributor.authorGültepe, M.
dc.contributor.authorCebeci, Bekir Sıtkı
dc.contributor.authorDinçtürk, Mehmet
dc.date.accessioned2024-07-12T21:04:43Z
dc.date.available2024-07-12T21:04:43Z
dc.date.issued2008en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractDuring acute ischaemia the N-terminal site of albumin is altered, reducing its binding capacity; the modified protein is termed ischaemia-modified albumin (IMA). IMA is a sensitive marker of acute myocardial ischaemia but its diagnostic value in chronic angina pectoris patients is unclear. We investigated changes in blood levels of IMA during myocardial perfusion scintigraphy in patients with chronic angina pectoris in a study including 26 male and 20 female patients, with mean age 60 years. Technetium 99m perfusion imaging detected myocardial ischaemia in 26 patients. Coronary angiography was carried out in these 26 ischaemic patients. Mean IMA values at rest and peak exercise were significantly higher in the ischaemic than the non-ischaemic group. All IMA values were considered negative for cardiac ischaemia. Peak exercise IMA was significantly lower than the pre-exercise level only in the non-ischaemic group. IMA measurements during myocardial perfusion scintigraphy are not helpful in the diagnosis of myocardial ischaemia in patients with stable angina pectoris.en_US
dc.identifier.citationCingozbay, B. Y., Ozmen, N., Canbolat, N., Aparci, M., Kardeşoğlu, E., Narin, Y., Gultepe, M., Cebeci, B. S. ve Dincturk, M. (2008). Diagnostic value of ischaemia-modified albumin for predicting myocardial ischaemia during myocardial perfusion scintigraphy. The Journal of international medical research, Sage Journals. 36(1), s. 147–151.en_US
dc.identifier.endpage151en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage147en_US
dc.identifier.urihttps://journals.sagepub.com/doi/10.1177/147323000803600118?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3824
dc.identifier.volume36en_US
dc.institutionauthorCingözbay, Bekir Yılmaz
dc.institutionauthorCingözbay, Bekir Yılmaz
dc.language.isoenen_US
dc.publisherSage Journalsen_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.isversionof10.1177/147323000803600118en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY01939
dc.subjectMyocardial ischaemiaen_US
dc.subjectDiagnosisen_US
dc.subjectAngina Pectorisen_US
dc.subjectIschaemia-modified albuminen_US
dc.subjectMyocardial perfusion scintigraphyen_US
dc.titleDiagnostic value of ischaemia-modified albumin for predicting myocardial ischaemia during myocardial perfusion scintigraphyen_US
dc.typeArticle
dspace.entity.typePublication

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