Alpha-fetoprotein and carcinoembryonic antigen in gastric carcinoma

Basit Öğe Kaydı
dc.authorid0000-0002-8335-1927en_US
dc.contributor.authorMelek, Erkişi
dc.contributor.authorFigen, Doran
dc.contributor.authorBurgut, Hüseyin Refik
dc.contributor.authorSalih, Çolakoğlu
dc.contributor.authorKaraer, P.
dc.contributor.authorVarinli, Seyhan
dc.date.accessioned2024-07-12T21:04:40Z
dc.date.available2024-07-12T21:04:40Z
dc.date.issued1994en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractFifty-four early stage gastric cancer patients were investigated for the presence of AFP and CEA. In their tumor specimens 9 patients showed AFP, 14 patients showed CEA and 9 patients showed AFP and CEA positivity by immunoperoxidase staining. Mean age was younger in AFP (+) patients (44.35 ± 8.4) than others (53.5 ± 8.0, p=0.0006). There was a significant correlation between the AFP and CEA positivity and stage of the disease (p=0.001, p=0.001). Lymphatic and/or venous invasion were more prominent in tumors with positive AFP staining (p=0.04) but serosal invasion was more frequent in CEA (+) tumors (p=0.05). The incidence of poorly differentiated tumors was high in AFP (+) tumors (p=0.034). Disease free survival (DFS) and overall survival (OS) were significantly shorter in patients with high serum AFP and CEA levels (p=0.0001). As conclusion AFP and CEA content of the tumor is a very important parameter in the management and prognosis of gastric cancer patients.en_US
dc.identifier.citationErkişi, M., Doran, F., Burgut, H. R., Colakoğlu, S., Karaer, P., ve Varinli, S. (1994). Alpha-fetoprotein and carcinoembryonic antigen in gastric carcinoma. Journal of Experimental and Clinical Cancer Research. 13(3), s. 253-256.en_US
dc.identifier.endpage256en_US
dc.identifier.issn0392-9078
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage253en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3813
dc.identifier.volume13en_US
dc.institutionauthorBurgut, Hüseyin Refik
dc.language.isoenen_US
dc.publisherSpringer Natureen_US
dc.relation.ispartofJournal of Experimental and Clinical Cancer Researchen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01897
dc.subjectAlpha-fetoproteinen_US
dc.subjectCarcinoembryonic antigenen_US
dc.subjectGastric canceren_US
dc.titleAlpha-fetoprotein and carcinoembryonic antigen in gastric carcinomaen_US
dc.typeArticle
dspace.entity.typePublication

Dosyalar

Koleksiyon

Tıp Fakültesi Koleksiyonu