Rapid fluid administration and the incidence of hypotension induced by spinal anesthesia and ephedrine requirement: the effect of crystalloid versus colloid coloading

dc.authorid0000-0002-8335-1927en_US
dc.contributor.authorÜnlügenç, Hakkı
dc.contributor.authorTurktan, Mediha
dc.contributor.authorEvruke, İsmail Cüneyt
dc.contributor.authorGündüz, Murat
dc.contributor.authorBurgut, Hüseyin Refik
dc.contributor.authorYapıcıoğlu Yıldıztaş, Hacer
dc.contributor.authorIşık, Geylan
dc.date.accessioned2024-07-12T21:10:15Z
dc.date.available2024-07-12T21:10:15Z
dc.date.issued2015en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractPurpose: Spinal anesthesia for caesarean delivery is often associated with hypotension. This study was conducted to evaluate the effects of rapid crystalloid (Lactated Ringer’s solution; LRS) or colloid (hydroxyethyl starch; HES) cohydration with a second intravenous access line on the incidence of hypotension and ephedrine requirement during spinal anesthesia for cesarean section. Methods: We studied 90 women with uncomplicated pregnancies undergoing elective cesarean section under spinal anesthesia. Intravenous access was established in all patients with two peripheral intravenous lines, the first being used for the baseline volume infusion. Immediately after induction of spinal anesthesia, LRS (Group L) or HES (Group C) infusions were started at the maximal possible rate via the second line in groups L and C respectively. In the third group (Group E) , patients received lactated Ringer’s solution at a ‘keep vein open’ rate to maintain the doubleblind nature. The incidence of hypotension, ephedrine requirements, total amount of volume and side effects were recorded. Results: The incidence of hypotension was significantly greater in group E than in groups L and C, and greater in group L than in group C (p<0.03 and p<0.01 respectively ). The total dose of ephedrine used to treat hypotension was significantly less in groups L and C than in group E (p<0.001 and p<0.001 respectively). Groups L and C received similar infusion volumes and doses of ephedrine. Conclusions: Giving either LR or HES coloading via a second IV line caused less hypotension and required less use of ephedrine compared to no coloading. There were no maternal or neonatal side effects.en_US
dc.identifier.citationÜnlügenç, H., Turktan, M., Evruke, İ. C., Gündüz, M., Burgut, H. R., Yapıcıoğlu Yıldızdaş, H. ve Işık, G. (2015). Rapid fluid administration and the incidence of hypotension induced by spinal anesthesia and ephedrine requirement: the effect of crystalloid versus colloid coloading. Middle East Journal of Anesthesiology. 23(3), s. 273-281.en_US
dc.identifier.endpage281en_US
dc.identifier.issn0544-0440
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage273en_US
dc.identifier.urihttps://www.aub.edu.lb/fm/Anesthesiology/meja/Pages/Aboutus.aspx
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4224
dc.identifier.volume23en_US
dc.institutionauthorBurgut, Hüseyin Refik
dc.language.isoenen_US
dc.publisherAmerican University of Beiruten_US
dc.relation.ispartofMiddle East Journal of Anesthesiologyen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY02950
dc.subjectAnesthetic techniques-subarachnoiden_US
dc.subjectPharmacology-agonists adrenergicen_US
dc.subjectFluid therapyen_US
dc.subjectFluids iven_US
dc.titleRapid fluid administration and the incidence of hypotension induced by spinal anesthesia and ephedrine requirement: the effect of crystalloid versus colloid coloadingen_US
dc.typeArticle
dspace.entity.typePublication

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