Effect of uncomplicated obesity on QT interval in young men

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dc.authorid0000-0002-2858-4023en_US
dc.authorid0000-0003-1407-5313en_US
dc.contributor.authorArslan, Erol
dc.contributor.authorYığıner, Ömer
dc.contributor.authorYavaşoğlu, İrfan
dc.contributor.authorKardeşoğlu, Ejder
dc.contributor.authorNalbant, Selim
dc.date.accessioned2024-07-12T21:11:00Z
dc.date.available2024-07-12T21:11:00Z
dc.date.issued2010en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractQT prolongation and obesity are associated with ventricular arrhythmia and sudden cardiac death. The relationship between uncomplicated obesity and QT interval prolongation is not clear. OBJECTIVES: The aim of the study was to investigate the effects of uncomplicated obesity on QT interval in young men. PATIENTS AND METHODS: A total of 122 men, including 59 obese patients and 63 controls, were recruited into the study. Patients with hypertension, diabetes mellitus, and ischemic heart disease were ineligible. Body mass index (BMI) of all patients was calculated. QT interval was measured from the precordial lead – V5, and corrected QT (QTC) was calculated using the Bazett’s formula. RESULTS: Mean age, BMI, and waist circumference (WC) of obese patients and controls were as follows: 22.0 ±3.0 years, 36.2 ±2.2 kg/m², and 114 ±8.1 cm; 22.6 ±2.9 years, 24.7 ±2.5 kg/m², and 81.6 ±7.5 cm, respectively. There was a statistically significant difference between the obese and control groups with regard to BMI and WC (P <0.001). Furthermore, statistically significant differences were observed between the 2 groups in terms of QTC (407.9 ±17.1 ms vs. 397.7 ±14.0 ms, respectively, P <0.001), systolic (126.9 ±8.2 mmHg vs. 114.2 ±11.1 mmHg, respectively, P <0.001) and diastolic blood pressure (78.3 ±4.5 mmHg vs. 66.9 ±10 mmHg, respectively, P <0.001). There was a positive correlation between QTC interval and both WC (r = 0.357, P <0.001) and BMI (r = 0.424, P <0.001). There was no association between QTC and blood pressure. CONCLUSIONS: Uncomplicated obesity in young men is associated with QT interval prolongation. Weight gain may inversely affect cardiac repolarization in uncomplicated obesity.en_US
dc.identifier.citationArslan, E., Yığıner, O., Yavaşoğlu, I., Özçelik, F., Kardeşoğlu, E. ve Nalbant, S. (2010). Effect of uncomplicated obesity on QT interval in young men. Polish Archives of Internal Medicine, Polish Society of Internal Medicine. 120(6), s. 209-213.en_US
dc.identifier.endpage213en_US
dc.identifier.issn0032-3772
dc.identifier.issn1897-9483
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage209en_US
dc.identifier.urihttps://www.mp.pl/paim/issue/article/927
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4312
dc.identifier.volume120en_US
dc.language.isoenen_US
dc.publisherPolish Society of Internal Medicineen_US
dc.relation.ispartofPolish Archives of Internal Medicineen_US
dc.relation.isversionof10.20452/pamw.927en_US
dc.relation.publicationcategoryUlusal Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.snmzKY03287
dc.subjectcorrected QTen_US
dc.subjectprolonged QT intervalen_US
dc.subjectuncomplicated obesityen_US
dc.titleEffect of uncomplicated obesity on QT interval in young menen_US
dc.typeArticle
dspace.entity.typePublication

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