Delirium-associated disulfiram and ethanol interactions

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dc.contributor.authorMirsal H.
dc.contributor.authorYalug I.
dc.contributor.authorTan D.
dc.contributor.authorStern T.A.
dc.contributor.authorKalyoncu A.
dc.contributor.authorPektas O.
dc.contributor.authorErdogan G.
dc.contributor.authorBeyazyürek M.
dc.date.accessioned2024-07-12T21:52:51Z
dc.date.available2024-07-12T21:52:51Z
dc.date.issued2005en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractBackground: Disulfiram, an agent used for the treatment of alcohol dependence, can exacerbate psychiatric syndromes (including psychosis, catatonia, delirium, depression, and mania) after extended use. However, delirium has yet to be reported following the short-term use of disulfiram in the setting of alcohol use. Objectives: We report a case with a neuropsychiatric presentation and discuss the prevention and the progression of delirium associated with an interaction of disulfiram and ethanol. Case Report: We report the case of a 51-year-old woman who developed disorganized speech, diminished communication, a decrease in appetite, and thoughts of suicide 10 days after she began taking disulfiram (250 mg/day), to which she added 1 glass of alcoholic beverage for 2 days. Delirium developed in association with an interaction between disulfiram and alcohol. The patient met DSM-IV criteria for major depressive disorder, alcohol dependence, and delirium. Discussion: Neuropsychiatric manifestations may develop in association with co-administration of disulfiram and alcohol; timely recognition and treatment are recommended. © Copyright 2005 Physicians Postgraduate Press, Inc.en_US
dc.identifier.doi10.4088/PCC.v07n0505
dc.identifier.endpage237en_US
dc.identifier.issn1523-5998
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-28244489276en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage235en_US
dc.identifier.urihttps://dx.doi.org/10.4088/PCC.v07n0505
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8436
dc.identifier.volume7en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherPhysicians Postgraduate Press Inc.en_US
dc.relation.ispartofPrimary Care Companion to the Journal of Clinical Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY03302
dc.titleDelirium-associated disulfiram and ethanol interactionsen_US
dc.typeArticle
dspace.entity.typePublication

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