Aortic elastic properties in patients with venous thromboembolism
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Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
Sage Journals
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Objectives: The relationship between venous thrombosis (VT) and atherosclerosis is controversial in recent studies. Aortic elastic properties have a predictive value in detecting early stages of atherosclerosis. The aim of this study is to evaluate the relationship between aortic elastic properties and VT. Methods: Elastic properties of aorta in patients with spontaneous VT, without history of known cardiovascular disease and cardiovascular risk factors (n: 31), and in healthy subjects without cardiovascular risk factors (n: 30) were compared. Elastic properties of the aorta were assessed with transthoracic echocardiography. Results: A significant increase in aortic stiffness index (6.5 ± 1.0 versus 6 ± 0.7, P = 0.03) and a significant decrease in aortic strain and aortic distensibility were found in patients with VT compared with healthy subjects (8.4 ± 7 versus 13 ± 8, P = 0.01, 4.9 ± 4.8 versus 6.5 ± 4.4, P = 0.03, respectively). Conclusions: Elastic properties of aorta in patients with spontaneous VT were impaired. These results may support the role of endothelial dysfunction in the pathogenesis of VT.
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Keywords
Journal or Series
Phlebology
WoS Q Value
Scopus Q Value
Q3
Volume
25
Issue
5
Citation
Duran, N. E., Oğuz, E., Duran, İ., Ayhan, A. C., Ertürk, E., Bayram, Z., Gürsoy, M. O., Biteker, M., Karavelioğlu, Y., Kaya, H. ve Özkan, M. (2010). Aortic elastic properties in patients with venous thromboembolism. Phlebology. 25(5), s. 246-251.