Prognosis of patients with seizures occurring in the first 2 years

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dc.authorid0000-0002-8335-1927en_US
dc.contributor.authorAltunbaşak, Şakir
dc.contributor.authorİncecik, Faruk
dc.contributor.authorHergüner, Özlem
dc.contributor.authorBurgut, Hüseyin Refik
dc.date.accessioned2024-07-12T21:04:38Z
dc.date.available2024-07-12T21:04:38Z
dc.date.issued2007en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractThe aim of this study is to determine the prognosis of patients with seizure onset from 1 to 24 months of age in respect to epilepsy, developmental outcome, and neurological status. It also aims to determine predictive factors regarding an unfavorable prognosis. Seventy-five patients were retrospectively analyzed. Univariate analysis revealed the following findings: (1) mental retardation at initial admission, abnormal neurological finding, infantile spasm, use of more than 1 antiepileptic drug, epileptic activity on electroencephalography (EEG) of neonatal seizure, and perinatal anoxia were significant risk factors with regard to developmental outcome; (2) mental retardation at initial admission, abnormal neurological finding, infantile spasm, use of more than 1 antiepileptic drug, epileptic activity on EEG, symptomatic etiology, history of neonatal seizure, and perinatal anoxia were significant risk factors regarding neurological status; and (3) mental retardation at initial admission, neurological abnormality, infantile spasm, use of more than 1 antiepileptic drug, epileptic activity on EEG, status epilepticus, symptomatic etiology, seizure frequency of more than once per week, history of perinatal anoxia, and neonatal seizure were significant risk factors regarding epilepsy prognosis. In addition, multivariate analysis revealed that neurological abnormality and use of more than 1 antiepileptic drug were significant for developmental outcome, that epileptic activity on EEG and use of more than 1 antiepileptic drug were significant for neurological status, and that perinatal anoxia, infantile spasm, and status epilepticus were significant for epilepsy prognosis. These findings suggest that neurological abnormality, use of more than 1 antiepileptic drug, infantile spasm, status epilepticus, and perinatal anoxia are unfavorable predictive risk factors regarding the prognosis of patients with seizures that have an onset from 1 to 24 months of age.en_US
dc.identifier.citationAltunbaşak, Ş., İncecik, F., Hergüner, Ö. ve Burgut, H. R. (2007). Prognosis of patients with seizures occurring in the first 2 years. Journal of Child Neurology. 22(3), s. 307-313.en_US
dc.identifier.endpage313en_US
dc.identifier.issue3en_US
dc.identifier.startpage307en_US
dc.identifier.urihttps://journals.sagepub.com/home/jcn
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3802
dc.identifier.volume22en_US
dc.institutionauthorBurgut, Hüseyin Refik
dc.language.isoenen_US
dc.publisherSage Publicationsen_US
dc.relation.ispartofJournal of Child Neurologyen_US
dc.relation.isversionof10.1177/0883073807300540en_US
dc.relation.publicationcategoryUlusal Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01833
dc.titlePrognosis of patients with seizures occurring in the first 2 yearsen_US
dc.typeArticle
dspace.entity.typePublication

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