The relationship between cholesterol levels and depression in the elderly

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dc.authorid0000-0002-8335-1927en_US
dc.contributor.authorErgün, Güney Özer
dc.contributor.authorUğuz, Sacit
dc.contributor.authorBozdemir, Nafiz
dc.contributor.authorGüzel, Rengin
dc.contributor.authorBurgut, Hüseyin Refik
dc.contributor.authorSaatçi, Esra
dc.contributor.authorAkpınar, Ersin
dc.date.accessioned2024-07-12T21:04:12Z
dc.date.available2024-07-12T21:04:12Z
dc.date.issued2004en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractObjective This study was undertaken to evaluate the possible association between low levels of serum cholesterol and depression in the elderly. Background The alteration of cholesterol content of synoptosomal membrane in response to low serum cholesterol levels has been shown to decrease the serotonin receptors in depressed patients. Previous studies suggest that low levels of serum cholesterol may be associated with the increased risk of depression in the elderly. Subjects and methods This was a cross?sectional study where 189 subjects over 65 years old of both sexes were enrolled. Serum total cholesterol, HDL?cholesterol (HDL?C), LDL?cholesterol (LDL?C), and triglycerides were measured. Cognitive functions were evaluated with mini mental state examination survey (MMSES) and depression was assessed with Structured Clinical Interview for DSM?IV Axis I Disorders (SCID?I). Results Of the 189 subjects, 42 were affected by depression. Low serum cholesterol level (cut?off ?160?mg/dl) as well as the levels of HDL?C, LDL?C and triglycerides were not associated with depression in older men or women. Conclusions In the present cross sectional study, there was no association between depression and low serum cholesterol levels after adjusted for confounding factors. Further studies are needed to clarify this suggestion with larger number of patients.en_US
dc.identifier.citationErgün, G. Ö., Uğuz, S., Bozdemir, N., Güzel, R., Burgut, H. R., Saatçi, E. ve Akpınar, E. (2004). The relationship between cholesterol levels and depression in the elderly. International Journal of Geriatric Psychiatry. 19(3), s. 291-296.en_US
dc.identifier.endpage296en_US
dc.identifier.issn0885-6230
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage291en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3764
dc.identifier.volume19en_US
dc.institutionauthorBurgut, Hüseyin Refik
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Geriatric Psychiatryen_US
dc.relation.isversionof10.1002/gps.1078en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01641
dc.titleThe relationship between cholesterol levels and depression in the elderlyen_US
dc.typeArticle
dspace.entity.typePublication

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