Comparison of COVID-19 Outcomes With Alpha-1 Antitrypsin Deficiency Prevalence in Europe: A Cross-Sectional Study
dc.authorid | Sezgin, Yılmaz/0000-0002-3626-0264 | en_US |
dc.authorid | KAPLAN, ASKIN KESKIN/0000-0003-4326-1529 | en_US |
dc.contributor.author | Sezgin, Yılmaz | |
dc.contributor.author | Becel, Sinan | |
dc.contributor.author | Kaplan, Askin K. | |
dc.date.accessioned | 2024-07-12T21:37:49Z | |
dc.date.available | 2024-07-12T21:37:49Z | |
dc.date.issued | 2023 | en_US |
dc.department | [Belirlenecek] | en_US |
dc.description.abstract | Introduction We hypothesized that the geographic distributions of COVID-19 and alpha-1 antitrypsin alleles prevalence are similar. We investigate whether there is a relationship between the geographical density of the COVID-19 pandemic and the distributions of alpha-1 antitrypsin alleles. Methods This research is a cross-sectional study. Alpha-1 antitrypsin PI*MS, PI*MZ, PI*SS, PI*SZ, and PI*ZZ genotypes frequencies of European countries were compared with the case and death data related to the COVID-19 pandemic as of March 1, 2022. Results A significant relationship was found between the rates of COVID-19 cases and the rates of individuals with alpha-1 antitrypsin PI*MS, PI*MZ, PI*SS, PI*SZ, and PI*ZZ genotypes allele in European countries. Conclusions The findings showed that the prevalence distribution of the alleles of the gene defect that causes alpha-1 antitrypsin insufficiency is related to the prevalence of COVID-19 pandemic data. | en_US |
dc.identifier.doi | 10.7759/cureus.34293 | |
dc.identifier.issn | 2168-8184 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.pmid | 36860224 | en_US |
dc.identifier.uri | https://doi.org/10.7759/cureus.34293 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12415/6954 | |
dc.identifier.volume | 15 | en_US |
dc.identifier.wos | WOS:000945749100014 | en_US |
dc.identifier.wosquality | N/A | en_US |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | en_US |
dc.publisher | Cureus Inc | en_US |
dc.relation.ispartof | Cureus Journal of Medical Science | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.snmz | KY04296 | |
dc.subject | Pandemia | en_US |
dc.subject | Europa | en_US |
dc.subject | Prevalence | en_US |
dc.subject | Alpha-1 Antitrypsin Deficiency | en_US |
dc.subject | Covid-19 | en_US |
dc.title | Comparison of COVID-19 Outcomes With Alpha-1 Antitrypsin Deficiency Prevalence in Europe: A Cross-Sectional Study | en_US |
dc.type | Article | |
dspace.entity.type | Publication |