Acute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course and prognosis

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dc.authorid0000-0003-1078-0445en_US
dc.contributor.authorGürsu, Meltem
dc.contributor.authorYeğenağa, Itır
dc.contributor.authorTuğlular, Serhan
dc.contributor.authorDursun, Belda
dc.contributor.authorBek, Sibel Gökçay
dc.contributor.authorBardak, Simge
dc.contributor.authorOnan, Engin
dc.contributor.authorDemir, Serap
dc.contributor.authorDerici, Ülver
dc.contributor.authorDoğukan, Ayhan
dc.contributor.authorSevinç, Mustafa
dc.contributor.authorKoçyiğit, İsmail
dc.contributor.authorAltun, Eda
dc.contributor.authorHaras, Ali Burak
dc.contributor.authorAltıparmak, Mehmet Rıza
dc.contributor.authorTombul, Zeki
dc.date.accessioned2024-07-12T21:02:07Z
dc.date.available2024-07-12T21:02:07Z
dc.date.issued2022en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground: In this study, we aimed to evaluate the etiology, comorbidities and outcome of acute kidney injury (AKI) in our country, and if there is, to demonstrate any potential differences in different geographical parts of the country. Methods: This prospective observational study was carried on by Acute Kidney Injury Working Group of Turkish Society of Nephrology. Demographical and clinical data of AKI patients at the time of diagnosis, at the 1 st week and 1 st , 3 rd and 6 th months were evaluated to determine patient and renal survival, and factors associated with prognosis. Results: 776 patients were included (54.7% male, median age: 67 years). Prerenal causes were more frequent, namely dehydration, heart failure and sepsis. 58.9% of patients had at least one renal etiology, most frequently nephrotoxic agent exposure. Etiologic factors were mostly similar through the country. 33.6% of patients needed renal replacement therapy. At the 6 th month of diagnosis, 29.5% of patients had complete, 34.1% had partial recovery, end stage kidney disease ensued in 9.5% and 24.1% died. Death rate was higher in patients from Eastern Anatolian region, those in intensive care unit, patients with prerenal, renal and postrenal etiologies together, stage-3 AKI, sepsis, cirrhosis, heart failure, malignancy, need for renal replacement therapy and those without chronic kidney disease. Conclusion: Physicians dealing with AKI should be alert against dehydration, heart failure and sepsis, nephrotoxic agent exposure while taking care of these patients. Being aware of the characteristics of AKI patients and outcomes in their country would help to prevent AKI and treating better.en_US
dc.identifier.citationGürsu, M., Yeğenağa, I. and at all. (2022). Acute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course and prognosis. BioMed Central Ltd., p.1-26.en_US
dc.identifier.endpage26en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3583
dc.institutionauthorYeğenağa, Itır
dc.language.isoenen_US
dc.publisherBioMed Central Ltden_US
dc.relation.ispartofBioMed Central Ltden_US
dc.relation.isversionof10.21203/rs.3.rs-1383569/v1en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY00425
dc.subjectAcuteen_US
dc.subjectEpidemiologicalen_US
dc.subjectEtiologyen_US
dc.subjectPrognosisen_US
dc.subjectTurkeyen_US
dc.titleAcute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course and prognosisen_US
dc.typeArticle
dspace.entity.typePublication

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