Risk factors predicting refractoriness in epileptic children with partial seizures

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dc.authorid0000-0002-8335-1927en_US
dc.contributor.authorAltunbaşak, Şakir
dc.contributor.authorHergüner, Özlem
dc.contributor.authorBurgut, Hüseyin Refik
dc.date.accessioned2024-07-12T21:04:38Z
dc.date.available2024-07-12T21:04:38Z
dc.date.issued2007en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractThe aim of this retrospective study was to determine the risk factors associated with intractability to therapy in childhood epilepsy. Fifty children with intractable epilepsy as evidenced by at least 1 epileptic fit per month were included in the study group, whereas the control group consisted of children who did not experience any recurrent seizure for at least 1 year at the time of the study. A ? 2 test was used to evaluate the relationship between the test variables for the 2 groups, and the estimated relative risk (odds ratio) for each variable was calculated. The risk factors were subsequently determined by logistic multiple regression analysis. Univariate analysis showed that mental retardation, neurological abnormality, neuroradiological abnormality, perinatal anoxia, neonatal convulsion, presence of status epilepticus, and symptomatic etiology were significant risk factors for the development of refractory epilepsy (P < .05). For multivariate logistic regression analysis, age at seizure onset, status epilepticus, mixed type of seizures, and history of frequent seizures (more than once a month) were all found to be significant and independent risk factors for refractory epilepsy, and the number of drugs used in the study group was significantly higher than that in the control group (P < .05). In line with these findings, it was concluded that children who present with epilepsy and have these risk factors should be referred to a center where epileptic surgery is carried out without delay.en_US
dc.identifier.citationAltunbaşak, S., Hergüner, Ö. ve Burgut, H. R. (2007). Risk factors predicting refractoriness in epileptic children with partial seizures. Journal of Child Neourology. 22(2), s. 195-199.en_US
dc.identifier.endpage199en_US
dc.identifier.issue2en_US
dc.identifier.startpage195en_US
dc.identifier.urihttps://journals.sagepub.com/doi/abs/10.1177/0883073807300304
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3801
dc.identifier.volume22en_US
dc.institutionauthorBurgut, Hüseyin Refik
dc.language.isoenen_US
dc.publisherSage Publicationsen_US
dc.relation.ispartofJournal of Child Neurologyen_US
dc.relation.isversionof10.1177/0883073807300304en_US
dc.relation.publicationcategoryUlusal Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01832
dc.titleRisk factors predicting refractoriness in epileptic children with partial seizuresen_US
dc.typeArticle
dspace.entity.typePublication

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