Radiation-induced liposarcoma of the retropharyngeal space

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dc.authorid0000-0001-7914-2201en_US
dc.contributor.authorDemir, Deniz
dc.contributor.authorKatırcıoğlu, Sami
dc.contributor.authorBilgiç, Bilge
dc.contributor.authorSüoğlu, Yusufhan
dc.contributor.authorDemir, Deniz
dc.date.accessioned2024-07-12T21:01:00Z
dc.date.available2024-07-12T21:01:00Z
dc.date.issued2006en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractLiposarcomas are the second most frequently encountered sarcomas that occur in soft tissue.1 Primary liposarcoma of the retropharyngeal space is rare. Recent reviews of the English-language literature identified only 3 cases of liposarcoma reported in retropharyngeal space. Results of the literature review show that there is no report of a radiation-induced liposarcoma occurring in the retro-pharyngeal space. We present the first case of liposarcoma of the retropharyngeal space; it occurred 10 years after radiation treatment for undifferentiated malignant tumor of the retropharynx. A 53-year-old man presented to our clinic with bilateral extensive swelling of his neck that had been present for 6 months. The patient did not smoke or drink alcohol. He had had dysphagia and dyspnea for 3 months, but he had no pain. His medical history began 23 years ago when he was referred for assessment of dysphagia and a foreign body sensation in his throat without swelling of his neck. According to his medical report, a transoral biopsy from the retropharyngeal mucosa was performed while he was under general anesthesia in another hospital. The pathology report was an undifferentiated malignant tumor. As a result of this histologic finding, he had received radiotherapy dose of 70 Gy and chemotherapy for 6 months. The patient complained of his previous symptoms again 10 years later. Endoscopic examination revealed a mass occupying the retropharyngeal space. This mass was removed through an external approach with the patient under general anesthesia. The histopathology of the specimen consisted of focal components of lipoma-like subtype of well-differentiated liposarcoma. These slides could not be obtained from the other hospital. During his admission to our clinic, a soft, nontender massive swelling of the neck bilaterally was discovered. Laryngoscopic examination showed a smooth sessile swelling of the posterior pharyngeal mass that obliterated the pharyngeal inlet extending from the velopharyngeal area to the cricopharyngeal junction below. Vocal cord motion was normal. No mucosal ulceration or necrosis was seen. There was no pooling of saliva in the pyriform fossae. A magnetic resonance scan reported extensive fatty tissue extending into the retropharyngeal and carotid spaces bilaterally containing septations and nodules that was a multilobulated and homogeneous fat density mass extending from the level of the velopharyngeal area to the level of the thoracic inlet (Fig 1).en_US
dc.identifier.citationDemir, D., Katırcıoğlu, S., Bilgiç, B. ve Süoğlu, Y. (2006). Radiation-induced liposarcoma of the retropharyngeal space. Otolaryngology–Head and Neck Surgery, Sage Journals. 134(6), s. 1060-1062.en_US
dc.identifier.endpage1062en_US
dc.identifier.issn1097-6817
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1060en_US
dc.identifier.urihttps://journals.sagepub.com/doi/10.1016/j.otohns.2005.03.043?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3438
dc.identifier.volume134en_US
dc.institutionauthorDemir, Deniz
dc.language.isoenen_US
dc.publisherSage Journalsen_US
dc.relation.ispartofOtolaryngology–Head and Neck Surgeryen_US
dc.relation.isversionof10.1016/j.otohns.2005.03.043en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY03186
dc.titleRadiation-induced liposarcoma of the retropharyngeal spaceen_US
dc.typeArticle
dspace.entity.typePublication

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