CT and 18F- FDG-PET-CT Findings in Secondary Adrenal Lymphoma with Pathologic Correlation

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dc.contributor.authorAltinmakas E.
dc.contributor.authorÜçışık-Keser F.E.
dc.contributor.authorMedeiros L.J.
dc.contributor.authorNg C.S.
dc.date.accessioned2024-07-12T21:44:12Z
dc.date.available2024-07-12T21:44:12Z
dc.date.issued2019en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractRationale and Objective: To evaluate computed tomography (CT)and positron emission tomography-computed tomography (PET-CT)imaging manifestations of lymphomas secondarily involving the adrenal gland. Materials and Methods: Seven patients (Five men, two women; median age [range], 66 years [34–75 years])with pathologically proven adrenal lymphoma were assessed retrospectively. Clinical findings, prior history of lymphoproliferative malignancy, CT (n = 7)and fludeoxyglucose positron emission tomography-computed tomography (18F-FDG-PET-CT)(n = 6)features were analyzed. Results: Six cases were diffuse large B-cell lymphoma, and one case was peripheral T-cell lymphoma. The longest diameter of the lesions ranged from 3.2 to 6.6 cm (median 4.3 cm). Six lesions were well-defined and one lesion was ill-defined. In five cases, an adreniform shape was preserved. No lesions contained fat, calcification or hemorrhage. Two lesions had necrosis on CT. Median (range)unenhanced CT density of six lesions was 31.8 (29.2–35.2)Hounsfield units. Following administration of IV contrast media (n = 6), three lesions enhanced homogenously whereas three enhanced heterogeneously. The median increase in attenuation was 35.1 Hounsfield units. Two patients had 15-minute delayed CT and they both demonstrated limited wash-out consistent with nonadenoma. Six patients had fludeoxyglucose positron emission tomography-computed tomography(18-F-FDG-PET-CT)and all lesions were fludeoxyglucose (FDG)avid with a median SUVmax of 18.6 (range: 10.3–49.2). Conclusion: Secondary adrenal lymphomas usually manifest as, large (>3 cm), well-defined, homogenously or slightly heterogeneously enhancing masses on CT with preserved adreniform shape. These lesions tend to show limited wash-out and high fludeoxyglucose (FDG)uptake. © 2018 The Association of University Radiologistsen_US
dc.identifier.doi10.1016/j.acra.2018.06.025
dc.identifier.endpagee114en_US
dc.identifier.issn1076-6332
dc.identifier.issue6en_US
dc.identifier.pmid30076085en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpagee108en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.acra.2018.06.025
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7693
dc.identifier.volume26en_US
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier USAen_US
dc.relation.ispartofAcademic Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00020
dc.subject18F-FDG-PET-CTen_US
dc.subjectAdrenalen_US
dc.subjectCTen_US
dc.subjectSecondary adrenal lymphomaen_US
dc.titleCT and 18F- FDG-PET-CT Findings in Secondary Adrenal Lymphoma with Pathologic Correlationen_US
dc.typeArticle
dspace.entity.typePublication

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